Molecular markers guiding thyroid cancer management

C Nylén, R Mechera, I Maréchal-Ross, V Tsang… - Cancers, 2020 - mdpi.com
The incidence of thyroid cancer is rapidly increasing, mostly due to the overdiagnosis and
overtreatment of differentiated thyroid cancer (TC). The increasing use of potent preclinical …

Efficacy and safety of larotrectinib in patients with TRK fusion-positive thyroid carcinoma

SG Waguespack, A Drilon, JJ Lin… - European journal of …, 2022 - academic.oup.com
Objective Larotrectinib is a highly selective tropomyosin receptor kinase (TRK) inhibitor with
demonstrated efficacy across various TRK fusion-positive solid tumours. We assessed the …

Raman Spectroscopy as a Potential Adjunct of Thyroid Nodule Evaluation: A Systematic Review

M Kujdowicz, D Januś… - International Journal of …, 2023 - mdpi.com
The incidence of thyroid nodules (TNs) is estimated at 36.5% and 23% in females and
males, respectively. A single thyroid nodule is usually detected during ultrasound …

Survival after hemithyroidectomy versus total thyroidectomy in non-high-risk differentiated thyroid cancer: population-based analysis

X Liu, CKH Wong, WWL Chan, ICH Au, EHM Tang… - BJS open, 2022 - academic.oup.com
Background The extent of thyroid surgery remains controversial for differentiated thyroid
cancers (DTCs) that measure more than 1 cm but are not considered high risk. This study …

FosB recruits KAT5 to potentiate the growth and metastasis of papillary thyroid cancer in a DPP4-dependent manner

J Du, L Fu, F Ji, C Wang, S Liu, X Qiu - Life Sciences, 2020 - Elsevier
Abstract Objective Dipeptidyl peptidase IV (DPP4) has been indicated as a possible
prognostic biomarker in papillary thyroid cancer (PTC). However, the mechanism of DPP4 …

Crocin treatment promotes the oxidative stress and apoptosis in human thyroid cancer cells FTC‐133 through the inhibition of STAT/JAK signaling pathway

Y Zhang, M Zhu, S Krishna Mohan… - Journal of Biochemical …, 2021 - Wiley Online Library
Thyroid cancer is the most frequent endocrine malignancy, which accounts for nearly 1% of
all the cancer worldwide. Crocin has a diverse biological function, such as anti‐cancer, anti …

Advances in molecular profiling and their potential influence on the extent of surgery in well-differentiated thyroid carcinoma (WDTC)

C Parpounas, V Constantinides - Life, 2023 - mdpi.com
Thyroid cancer surgery has evolved dramatically with advances in our understanding of the
biological behaviour of WDTC. Molecular profiling is shedding light on the subset that may …

FOXP2 regulates thyroid cancer cell proliferation and apoptosis via transcriptional activation of RPS6KA6

F Yang, Z Xiao, S Zhang - … and Therapeutic Medicine, 2022 - spandidos-publications.com
The transcription factor, forkhead box P2 (FOXP2) has tumor‑suppressive effects in several
types of cancer. However, the regulatory role and underlying mechanism of FOXP2 in …

Primary cell cultures for the personalized therapy in aggressive thyroid cancer of follicular origin

P Fallahi, SM Ferrari, G Elia, F Ragusa… - Seminars in Cancer …, 2022 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignancy. More than 90% of TC is
represented by differentiated TC (DTC) arising from the follicular thyroid cells. DTC includes …

Circular RNAs and thyroid cancer: Closed molecules, open possibilities

BM Shifman, NM Platonova, EV Vasilyev… - Critical Reviews in …, 2022 - Elsevier
Thyroid neoplasms requiring differential diagnosis between thyroid cancer and benign
tumors can be detected in more than half of the healthy population. A generally accepted …