Cx26 heterozygous mutations cause hyperacusis-like hearing oversensitivity and increase susceptibility to noise

LM Liu, C Liang, J Chen, S Fang, HB Zhao - Science Advances, 2023 - science.org
Gap junction gene GJB2 (Cx26) mutations cause> 50% of nonsyndromic hearing loss. Its
recessive hetero-mutation carriers, who have no deafness, occupy~ 10 to 20% of the …

Zinc deficiency triggers hearing loss by reducing ribbon synapses of inner hair cells in CBA/N mice

M Shim, J Yi, JH Pak, JW Chung - Biochemical and Biophysical Research …, 2024 - Elsevier
Zinc plays a vital role in our metabolism, encompassing antioxidant regulation, immune
response, and auditory function. Several studies have reported that zinc levels correlate with …

High-frequency hearing vulnerability associated with the different supporting potential of Hensen's cells: SMART-Seq2 RNA sequencing

Y Yu, Y Li, C Wen, F Yang, X Chen, W Yi, L Deng… - BioScience …, 2024 - jstage.jst.go.jp
Hearing loss is the third most prevalent physical condition affecting communication, well-
being, and healthcare costs. Sensorineural hearing loss often occurs first in the high …

[HTML][HTML] Potential mechanisms of Hearing Loss due to impaired Potassium Circulation in the Organ of Corti

G Spitzmaul, E Rías, L Dionisio - Updates on Hearing Loss and its …, 2023 - intechopen.com
Hearing loss (HL) is a common condition that significantly affects an individual's quality of
life. Impaired potassium circulation in the organ of Corti (OC), including the movement of …

Lateral olivocochlear neurons modulate cochlear responses to noise exposure

A Sitko, M Frank, G Romero, L Goodrich - bioRxiv, 2024 - biorxiv.org
The sense of hearing originates in the cochlea, which detects sounds across dynamic
sensory environments. Like other peripheral organs, the cochlea is subjected to …

Efferent Control in Musicians: A Review

F Acuña, R Jeria, E Pavez, E Aguilar-Vidal - Audiology Research, 2023 - mdpi.com
It is widely established that musicians possess a higher level in certain auditory perceptual
abilities when compared to non-musicians. This improvement may be mediated, at least in …

ATP-gated P2x7 receptor is a major channel type at type II auditory nerves and required for hearing sensitivity efferent controlling and noise protection

C Liang, TY Zhai, S Fang, J Chen, LM Liu, N Yu… - bioRxiv, 2024 - biorxiv.org
Hearing sensitivity and noise protection are mediated and determined by negative feedback
of the cochlear efferent system. Type II auditory nerves (ANs) innervate outer hair cells …

Cx26 heterozygous mutations cause hyperacusis-like hearing sensitivity enhancement and increase susceptibility to noise

LM Liu, C Liang, J Chen, S Fang, HB Zhao - bioRxiv, 2022 - biorxiv.org
Gap junction gene GJB2 (Cx26) mutations cause> 50% of nonsyndromic hearing loss. Its
recessive hetero-mutation carriers, who have no deafness, occupy∼ 10-20% of the general …

Rol de los canales Kv7. 4 en la sordera de progresión lenta DFNA2

C Carignano - 2022 - repositoriodigital.uns.edu.ar
La recirculación del potasio (K+) es un proceso indispensable para la audición, que tiene
lugar en el órgano de Corti (OC). Ante la presencia de estímulos sonoros, el K+ ingresa a …

[引用][C] Changes in Auditory Phase-Locking with Medial Olivocochlear Unmasking

K Amirapu - 2023 - ResearchSpace@ Auckland