[HTML][HTML] Seventy years of Chlamydia vaccine research–limitations of the past and directions for the future
S Phillips, BL Quigley, P Timms - Frontiers in microbiology, 2019 - frontiersin.org
Chlamydia is a major bacterial pathogen that infects humans, as well as a wide range of
animals, including marsupials, birds, cats, pigs, cattle, and sheep. Antibiotics are the only …
animals, including marsupials, birds, cats, pigs, cattle, and sheep. Antibiotics are the only …
Genital Chlamydia trachomatis: understanding the roles of innate and adaptive immunity in vaccine research
S Vasilevsky, G Greub… - Clinical microbiology …, 2014 - Am Soc Microbiol
Chlamydia trachomatis is the leading cause of bacterial sexually transmitted disease
worldwide, and despite significant advances in chlamydial research, a prophylactic vaccine …
worldwide, and despite significant advances in chlamydial research, a prophylactic vaccine …
Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens
NPH Knudsen, A Olsen, C Buonsanti, F Follmann… - Scientific reports, 2016 - nature.com
The majority of vaccine candidates in clinical development are highly purified proteins and
peptides relying on adjuvants to enhance and/or direct immune responses. Despite the …
peptides relying on adjuvants to enhance and/or direct immune responses. Despite the …
Development status and future prospects for a vaccine against Chlamydia trachomatis infection
Chlamydia trachomatis continues to be the most commonly reported sexually transmitted
bacterial infection in many countries with more than 100 million new cases estimated …
bacterial infection in many countries with more than 100 million new cases estimated …
[HTML][HTML] Induction of partial immunity in both males and females is sufficient to protect females against sexual transmission of Chlamydia
Sexually transmitted Chlamydia trachomatis causes infertility, and because almost 90% of
infections are asymptomatic, a vaccine is required for its eradication. Mathematical modeling …
infections are asymptomatic, a vaccine is required for its eradication. Mathematical modeling …
Prophylactic and therapeutic vaccination protects sperm health from Chlamydia muridarum-induced abnormalities
Chlamydia is the most common bacterial sexually transmitted infection worldwide and it is
widely acknowledged that controlling the rampant community transmission of this infection …
widely acknowledged that controlling the rampant community transmission of this infection …
[HTML][HTML] Enhanced clearance of C. muridarum infection using azithromycin-loaded liposomes
Chlamydia trachomatis is an intracellular bacterium which infects around 129 million people
annually. Despite similar infection rates between sexes, most research investigating the …
annually. Despite similar infection rates between sexes, most research investigating the …
Future of human Chlamydia vaccine: potential of self-adjuvanting biodegradable nanoparticles as safe vaccine delivery vehicles
Introduction: There is a persisting global burden and considerable public health challenge
by the plethora of ocular, genital and respiratory diseases caused by members of the Gram …
by the plethora of ocular, genital and respiratory diseases caused by members of the Gram …
Hematogenous dissemination of Chlamydia muridarum from the urethra in macrophages causes testicular infection and sperm DNA damage
The incidence of Chlamydia infection, in both females and males, is increasing worldwide.
Male infections have been associated clinically with urethritis, epididymitis, and orchitis …
Male infections have been associated clinically with urethritis, epididymitis, and orchitis …
Chronic testicular Chlamydia muridarum infection impairs mouse fertility and offspring development
ER Bryan, KA Redgrove, AR Mooney… - Biology of …, 2020 - academic.oup.com
With approximately 131 million new genital tract infections occurring each year, Chlamydia
is the most common sexually transmitted bacterial pathogen worldwide. Male and female …
is the most common sexually transmitted bacterial pathogen worldwide. Male and female …