[HTML][HTML] Ventilator-associated pneumonia in adults: a narrative review

L Papazian, M Klompas, CE Luyt - Intensive care medicine, 2020 - Springer
Ventilator-associated pneumonia (VAP) is one of the most frequent ICU-acquired infections.
Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic …

[HTML][HTML] Hospital-acquired pneumonia in ICU

M Leone, L Bouadma, B Bouhemad, O Brissaud… - … Critical Care & Pain …, 2018 - Elsevier
Abstract The French Society of Anesthesia and Intensive Care Medicine and the French
Society of Intensive Care edited guidelines focused on hospital-acquired pneumonia (HAP) …

[HTML][HTML] Update on ventilator-associated pneumonia

JF Timsit, W Esaied, M Neuville, L Bouadma… - …, 2017 - ncbi.nlm.nih.gov
Ventilator-associated pneumonia (VAP) is the most frequent life-threatening nosocomial
infection in intensive care units. The diagnostic is difficult because radiological and clinical …

[HTML][HTML] Epidemiology, treatment, and prevention of nosocomial bacterial pneumonia

SS Jean, YC Chang, WC Lin, WS Lee… - Journal of clinical …, 2020 - mdpi.com
Septicaemia likely results in high case-fatality rates in the present multidrug-resistant (MDR)
era. Amongst them are hospital-acquired pneumonia (HAP) and ventilator-associated …

Inhaled amikacin adjunctive to intravenous standard-of-care antibiotics in mechanically ventilated patients with Gram-negative pneumonia (INHALE): a double-blind …

MS Niederman, J Alder, M Bassetti… - The Lancet Infectious …, 2020 - thelancet.com
Background Treatment of ventilated pneumonia is often unsuccessful, even when patients
are treated according to established guidelines. Therefore, we aimed to investigate the …

[HTML][HTML] Advances in antibiotic therapy in the critically ill

JL Vincent, M Bassetti, B François, G Karam, J Chastre… - Critical Care, 2016 - Springer
Infections occur frequently in critically ill patients and their management can be challenging
for various reasons, including delayed diagnosis, difficulties identifying causative …

Inhaled antibiotics for gram-negative respiratory infections

E Wenzler, DR Fraidenburg, T Scardina… - Clinical microbiology …, 2016 - Am Soc Microbiol
Gram-negative organisms comprise a large portion of the pathogens responsible for lower
respiratory tract infections, especially those that are nosocomially acquired, and the rate of …

[HTML][HTML] Optimizing antimicrobial drug dosing in critically ill patients

P Póvoa, P Moniz, JG Pereira, L Coelho - Microorganisms, 2021 - mdpi.com
A fundamental step in the successful management of sepsis and septic shock is early
empiric antimicrobial therapy. However, for this to be effective, several decisions must be …

[HTML][HTML] Antimicrobials for the treatment of drug-resistant Acinetobacter baumannii pneumonia in critically ill patients: a systemic review and Bayesian network meta …

SY Jung, SH Lee, SY Lee, S Yang, H Noh, EK Chung… - Critical Care, 2017 - Springer
Background An optimal therapy for the treatment of pneumonia caused by drug-resistant
Acinetobacter baumannii remains unclear. This study aims to compare various antimicrobial …

Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis

C Sole-Lleonart, JJ Rouby, S Blot, G Poulakou… - …, 2017 - pubs.asahq.org
Background Nebulization of antiinfective agents is a common but unstandardized practice in
critically ill patients. Methods A systematic review of 1,435 studies was performed in adults …