Insulin-like peptides and cross-talk with other factors in the regulation of insect metabolism
S Chowański, K Walkowiak-Nowicka, M Winkiel… - Frontiers in …, 2021 - frontiersin.org
The insulin-like peptide (ILP) and insulin-like growth factor (IGF) signalling pathways play a
crucial role in the regulation of metabolism, growth and development, fecundity, stress …
crucial role in the regulation of metabolism, growth and development, fecundity, stress …
Insulin resistance at the crossroad of Alzheimer disease pathology: A review
J Berlanga-Acosta, G Guillén-Nieto… - Frontiers in …, 2020 - frontiersin.org
Insulin plays a major neuroprotective and trophic function for cerebral cell population, thus
countering apoptosis, beta-amyloid toxicity, and oxidative stress; favoring neuronal survival; …
countering apoptosis, beta-amyloid toxicity, and oxidative stress; favoring neuronal survival; …
Crosstalk between Nutrition, Insulin, Juvenile Hormone, and Ecdysteroid Signaling in the Classical Insect Model, Rhodnius prolixus
The rigorous balance of endocrine signals that control insect reproductive physiology is
crucial for the success of egg production. Rhodnius prolixus, a blood-feeding insect and …
crucial for the success of egg production. Rhodnius prolixus, a blood-feeding insect and …
Assessing the evolutionary lability of insulin signalling in the regulation of nutritional plasticity across traits and species of horned dung beetles
Nutrition‐dependent growth of sexual traits is a major contributor to phenotypic diversity, and
a large body of research documents insulin signalling as a major regulator of nutritional …
a large body of research documents insulin signalling as a major regulator of nutritional …
Complex evolution of insect insulin receptors and homologous decoy receptors, and functional significance of their multiplicity
V Smýkal, M Pivarči, J Provazník… - Molecular Biology …, 2020 - academic.oup.com
Evidence accumulates that the functional plasticity of insulin and insulin-like growth factor
signaling in insects could spring, among others, from the multiplicity of insulin receptors …
signaling in insects could spring, among others, from the multiplicity of insulin receptors …
Neofunctionalization of a second insulin receptor gene in the wing-dimorphic planthopper, Nilaparvata lugens
WH Xue, N Xu, SJ Chen, XY Liu, JL Zhang… - PLoS Genetics, 2021 - journals.plos.org
A single insulin receptor (InR) gene has been identified and extensively studied in model
species ranging from nematodes to mice. However, most insects possess additional copies …
species ranging from nematodes to mice. However, most insects possess additional copies …
The insulin signaling pathway a century after its discovery: sexual dimorphism in insulin signaling
JP Álvarez-Rendón, JM Murillo-Maldonado… - General and …, 2023 - Elsevier
Since practically a century ago, the insulin pathway was discovered in both vertebrates and
invertebrates, implying an evolutionarily ancient origin. After a century of research, it is now …
invertebrates, implying an evolutionarily ancient origin. After a century of research, it is now …
Structural models of viral insulin‐like peptides and their analogs
B Gorai, H Vashisth - Proteins: Structure, Function, and …, 2023 - Wiley Online Library
The insulin receptor (IR), the insulin‐like growth factor‐1 receptor (IGF1R), and the
insulin/IGF1 hybrid receptors (hybR) are homologous transmembrane receptors. The …
insulin/IGF1 hybrid receptors (hybR) are homologous transmembrane receptors. The …
Evolution of regulatory mechanisms underlying nutritionresponsive plasticity in insects
S Casasa - Frontiers in Ecology and Evolution, 2024 - frontiersin.org
Phenotypic plasticity is a fundamental property of developing organisms and is thought to
play an important role in diversification. Plastic responses themselves are remarkably …
play an important role in diversification. Plastic responses themselves are remarkably …
Characterization and Expression Analysis of Insulin Growth Factor Binding Proteins (IGFBPs) in Pacific White Shrimp Litopenaeus vannamei
Y Pang, X Zhang, J Yuan, X Zhang, J Xiang… - International Journal of …, 2021 - mdpi.com
The insulin signaling (IIS) pathway plays an important role in the metabolism, growth,
development, reproduction, and longevity of an organism. As a key member of the IIS …
development, reproduction, and longevity of an organism. As a key member of the IIS …