A comprehensive review on carotenoids in foods and feeds: status quo, applications, patents, and research needs

AJ Meléndez-Martínez, AI Mandić, F Bantis… - Critical Reviews in …, 2022 - Taylor & Francis
Carotenoids are isoprenoids widely distributed in foods that have been always part of the
diet of humans. Unlike the other so-called food bioactives, some carotenoids can be …

Metabolomics in diabetes and diabetic complications: insights from epidemiological studies

Q Jin, RCW Ma - Cells, 2021 - mdpi.com
The increasing prevalence of diabetes and its complications, such as cardiovascular and
kidney disease, remains a huge burden globally. Identification of biomarkers for the …

Methods of integrating data to uncover genotype–phenotype interactions

MD Ritchie, ER Holzinger, R Li… - Nature Reviews …, 2015 - nature.com
Recent technological advances have expanded the breadth of available omic data, from
whole-genome sequencing data, to extensive transcriptomic, methylomic and metabolomic …

A tutorial review: Metabolomics and partial least squares-discriminant analysis–a marriage of convenience or a shotgun wedding

PS Gromski, H Muhamadali, DI Ellis, Y Xu, E Correa… - Analytica chimica …, 2015 - Elsevier
The predominance of partial least squares-discriminant analysis (PLS-DA) used to analyze
metabolomics datasets (indeed, it is the most well-known tool to perform classification and …

Sampling root exudates–mission impossible?

E Oburger, DL Jones - Rhizosphere, 2018 - Elsevier
Accurate information about the quantity, quality and spatiotemporal dynamics of metabolite
release from plant roots is vital to understanding the functional significance of root exudates …

Foliar spray of TiO2 nanoparticles prevails over root application in reducing Cd accumulation and mitigating Cd-induced phytotoxicity in maize (Zea mays L.)

J Lian, L Zhao, J Wu, H Xiong, Y Bao, A Zeb, J Tang… - Chemosphere, 2020 - Elsevier
Cadmium (Cd) pollution is considered one of the global environmental issues due to its
adverse effects on plant and human health. With the rapid development of nanotechnology …

Do polystyrene nanoplastics affect the toxicity of cadmium to wheat (Triticum aestivum L.)?

J Lian, J Wu, A Zeb, S Zheng, T Ma, F Peng… - Environmental …, 2020 - Elsevier
There has been an increase on the research of microplastics (< 5 mm in diameter) as
carriers for toxic chemicals to evaluate their risks for human health and environment, but …

Omics approaches for the assessment of biological responses to nanoparticles

Y Abdelkader, L Perez-Davalos, R LeDuc… - Advanced Drug Delivery …, 2023 - Elsevier
Nanotechnology has enabled the development of innovative therapeutics, diagnostics, and
drug delivery systems. Nanoparticles (NPs) can influence gene expression, protein …

Applications of machine learning in metabolomics: Disease modeling and classification

A Galal, M Talal, A Moustafa - Frontiers in genetics, 2022 - frontiersin.org
Metabolomics research has recently gained popularity because it enables the study of
biological traits at the biochemical level and, as a result, can directly reveal what occurs in a …

Analysis of metabolomic data: tools, current strategies and future challenges for omics data integration

A Cambiaghi, M Ferrario… - Briefings in bioinformatics, 2017 - academic.oup.com
Metabolomics is a rapidly growing field consisting of the analysis of a large number of
metabolites at a system scale. The two major goals of metabolomics are the identification of …