Riboswitches: From living biosensors to novel targets of antibiotics
Riboswitches are generally located in 5′-UTR region of mRNAs and specifically bind small
ligands. Following ligand binding, gene expression is controlled mostly by transcription …
ligands. Following ligand binding, gene expression is controlled mostly by transcription …
From petri dish to patient: bioavailability estimation and mechanism of action for antimicrobial and immunomodulatory natural products
NJ Sadgrove, GL Jones - Frontiers in Microbiology, 2019 - frontiersin.org
The new era of multidrug resistance of pathogens against frontline antibiotics has
compromised the immense therapeutic gains of the 'golden age,'stimulating a resurgence in …
compromised the immense therapeutic gains of the 'golden age,'stimulating a resurgence in …
Gentamicin B1 is a minor gentamicin component with major nonsense mutation suppression activity
A Baradaran-Heravi, J Niesser, AD Balgi, K Choi… - Proceedings of the …, 2017 - JSTOR
Nonsense mutations underlie about 10% of rare genetic disease cases. They introduce a
premature termination codon (PTC) and prevent the formation of full-length protein …
premature termination codon (PTC) and prevent the formation of full-length protein …
Development of a new oligonucleotide block location-based feature extraction (BLBFE) method for the classification of riboswitches
As knowledge of genetics and genome elements increases, the demand for the
development of bioinformatics tools for analyzing these data is raised. Riboswitches are …
development of bioinformatics tools for analyzing these data is raised. Riboswitches are …
[HTML][HTML] Development of a new sequential block finding strategy for detection of conserved sequences in riboswitches
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Introduction: Some non-coding RNAs have an important role in the regulation of gene …
Introduction: Some non-coding RNAs have an important role in the regulation of gene …
Classification of Riboswitch Families Using Block Location-Based Feature Extraction (BLBFE) Method
Purpose: Riboswitches are special non-coding sequences usually located in mRNAs' un-
translated regions and regulate gene expression and consequently cellular function …
translated regions and regulate gene expression and consequently cellular function …
Aptamer-based biosensing of bioactive compounds: towards the rational screening of metagenomic libraries
C Ocasión Martínez - 2021 - repositorio.uniandes.edu.co
Resumen en español Los estudios de metagenómica han sido prometedores porque han
conducido al descubrimiento de nuevos bioproductos como enzimas y metabolitos. Sin …
conducido al descubrimiento de nuevos bioproductos como enzimas y metabolitos. Sin …