Osteoarthritis (OA) is the most common joint disorder and affects approximately half of the
aged population. Current treatments for OA are largely palliative until the articular cartilage …

Cellular senescence is a state of stable proliferation arrest of cells. The senescence pathway
has many beneficial effects and is seen to be activated in damaged/stressed cells, as well as …

Osteoarthritis (OA) is a growing public health problem across the globe, affecting more than
half of the over 65 population. In the past, OA was considered a wear and tear disease …

Altered expression and function of the transcription factor cyclic AMP response-binding
protein (CREB) has been identified to play an important role in cancer and is associated with …

Osteoarthritis (OA) was once defined as a non-inflammatory arthropathy, but it is now well-
recognized that there is a major inflammatory component to this disease. In addition to …

Articular chondrocytes are quiescent, fully differentiated cells responsible for the
homeostasis of adult articular cartilage by maintaining cellular survival functions and the fine …

Osteoarthritis (OA) is closely associated with aging, but its underlying mechanism is unclear.
Recent publications were reviewed to elucidate the connection between aging and OA. With …

Aging processes and the development of osteoarthritis : Current Opinion in Rheumatology
Aging processes and the development of osteoarthritis : Current Opinion in Rheumatology Log …

Osteoarthritis represents the most frequently diagnosed condition of the musculoskeletal
system and accounts for a high amount of direct and indirect socioeconomic costs …

Objective The aim of this study was to characterize the genome‐wide DNA methylation
profile of chondrocytes from knee and hip cartilage obtained from patients with osteoarthritis …