Current understanding of the right ventricle structure and function in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a disease resulting in increased right ventricular
(RV) afterload and RV remodeling. PAH results in altered RV structure and function at …
(RV) afterload and RV remodeling. PAH results in altered RV structure and function at …
A contemporary look at biomechanical models of myocardium
Understanding and predicting the mechanical behavior of myocardium under healthy and
pathophysiological conditions are vital to developing novel cardiac therapies and promoting …
pathophysiological conditions are vital to developing novel cardiac therapies and promoting …
Angiotensin receptor‐neprilysin inhibition attenuates right ventricular remodeling in pulmonary hypertension
D Sharifi Kia, E Benza, TN Bachman… - Journal of the …, 2020 - Am Heart Assoc
Background Pulmonary hypertension (PH) results in increased right ventricular (RV)
afterload and ventricular remodeling. Sacubitril/valsartan (sac/val) is a dual acting drug …
afterload and ventricular remodeling. Sacubitril/valsartan (sac/val) is a dual acting drug …
An image-driven micromechanical approach to characterize multiscale remodeling in infarcted myocardium
Myocardial infarction (MI) is accompanied by the formation of a fibrotic scar in the left
ventricle (LV) and initiates significant alterations in the architecture and constituents of the …
ventricle (LV) and initiates significant alterations in the architecture and constituents of the …
[HTML][HTML] Mechanics of pulmonary airways: linking structure to function through constitutive modeling, biochemistry, and histology
Breathing involves fluid-solid interactions in the lung; however, the lack of experimental data
inhibits combining the mechanics of air flow to airway deformation, challenging the …
inhibits combining the mechanics of air flow to airway deformation, challenging the …
A machine learning model to estimate myocardial stiffness from EDPVR
In-vivo estimation of mechanical properties of the myocardium is essential for patient-
specific diagnosis and prognosis of cardiac disease involving myocardial remodeling …
specific diagnosis and prognosis of cardiac disease involving myocardial remodeling …
Simulation of the 3D hyperelastic behavior of ventricular myocardium using a finite-element based neural-network approach
High-fidelity cardiac models using attribute-rich finite element based models have been
developed to a very mature stage. However, such finite-element based approaches remain …
developed to a very mature stage. However, such finite-element based approaches remain …
Right ventricular myocardial mechanics: Multi-modal deformation, microstructure, modeling, and comparison to the left ventricle
The right ventricular myocardium, much like the rest of the right side of the heart, has been
consistently understudied. Presently, little is known about its mechanics, its microstructure …
consistently understudied. Presently, little is known about its mechanics, its microstructure …
Biomechanical and hemodynamic measures of right ventricular diastolic function: Translating tissue biomechanics to clinical relevance
S Jang, RR Vanderpool… - Journal of the …, 2017 - Am Heart Assoc
Background Right ventricular (RV) diastolic function has been associated with outcomes for
patients with pulmonary hypertension; however, the relationship between biomechanics and …
patients with pulmonary hypertension; however, the relationship between biomechanics and …
Transmural remodeling of right ventricular myocardium in response to pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) imposes substantial pressure overload on the right
ventricular free wall (RVFW), leading to myofiber hypertrophy and remodeling of its collagen …
ventricular free wall (RVFW), leading to myofiber hypertrophy and remodeling of its collagen …