Small animal PET: a review of what we have done and where we are going

RS Miyaoka, AL Lehnert - Physics in Medicine & Biology, 2020 - iopscience.iop.org
Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

Innovations in small-animal PET instrumentation

AL Lehnert, RS Miyaoka - PET clinics, 2024 - pet.theclinics.com
There is always a balance to be struck when designing PET systems; overall performance
depends on spatial resolution, detection sensitivity, and timing performance, all of which are …

A novel single-ended readout depth-of-interaction PET detector fabricated using sub-surface laser engraving

H Uchida, T Sakai, H Yamauchi… - Physics in Medicine …, 2016 - iopscience.iop.org
We propose a novel scintillation detector design for positron emission tomography (PET),
which has depth of interaction (DOI) capability and uses a single-ended readout scheme …

Novel laser‐processed CsI: Tl detector for SPECT

H Sabet, L Bläckberg, D Uzun‐Ozsahin… - Medical …, 2016 - Wiley Online Library
Purpose: The aim of this work is to demonstrate the feasibility of a novel technique for
fabrication of high spatial resolution CsI: Tl scintillation detectors for single photon emission …

A depth-of-interaction PET detector using a stair-shaped reflector arrangement and a single-ended scintillation light readout

JW Son, MS Lee, JS Lee - Physics in Medicine & Biology, 2016 - iopscience.iop.org
Positron emission tomography (PET) detectors with the ability to encode depth-of-interaction
(DOI) information allow us to simultaneously improve the spatial resolution and sensitivity of …

A novel read-out electronics design based on 1-bit sigma-delta modulation

Z Zhao, Q Huang, Z Gong, Z Su… - … on Nuclear Science, 2017 - ieeexplore.ieee.org
The conventional front-end electronics for PET imaging consist of an energy circuit and a
timing circuit. A single channel in front-end electronics typically requires several amplifiers …

An edge‐readout, multilayer detector for positron emission tomography

X Li, M Ruiz‐Gonzalez, LR Furenlid - Medical physics, 2018 - Wiley Online Library
Purpose We present a novel gamma‐ray‐detector design based on total internal reflection
(TIR) of scintillation photons within a crystal that addresses many limitations of traditional …

Light spread manipulation in scintillators using laser induced optical barriers

L Bläckberg, M Moebius, G El Fakhri… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
We are using the laser induced optical barriers (LIOBs) technique to fabricate scintillator
detectors with combined performance characteristics of the two standard detector types …

A layered single-side readout depth of interaction time-of-flight-PET detector

L Bläckberg, S Sajedi, G El Fakhri… - Physics in Medicine & …, 2021 - iopscience.iop.org
We are exploring a scintillator-based PET detector with potential of high sensitivity, depth of
interaction (DOI) capability, and timing resolution, with single-side readout. Our design …

Simulation study of light transport in laser-processed LYSO: Ce detectors with single-side readout

L Bläckberg, G El Fakhri, H Sabet - Physics in Medicine & Biology, 2017 - iopscience.iop.org
A tightly focused pulsed laser beam can locally modify the crystal structure inside the bulk of
a scintillator. The result is incorporation of so-called optical barriers with a refractive index …