Review of recent developments in GC–MS approaches to metabolomics-based research

DJ Beale, FR Pinu, KA Kouremenos, MM Poojary… - Metabolomics, 2018 - Springer
Background Metabolomics aims to identify the changes in endogenous metabolites of
biological systems in response to intrinsic and extrinsic factors. This is accomplished …

A critical review on exploiting the pharmaceutical potential of plant endophytic fungi

S Gupta, P Chaturvedi, MG Kulkarni… - Biotechnology advances, 2020 - Elsevier
The escalating demand for secondary metabolites in international markets poses a severe
threat to many plant species. An unscrupulous collection is also the immediate challenge to …

HMDB 4.0: the human metabolome database for 2018

DS Wishart, YD Feunang, A Marcu, AC Guo… - Nucleic acids …, 2018 - academic.oup.com
Abstract The Human Metabolome Database or HMDB (www. hmdb. ca) is a web-enabled
metabolomic database containing comprehensive information about human metabolites …

Nontarget screening with high resolution mass spectrometry in the environment: ready to go?

J Hollender, EL Schymanski, HP Singer, PL Ferguson - 2017 - ACS Publications
The vast, diverse universe of organic pollutants is a formidable challenge for environmental
sciences, engineering, and regulation. Nontarget screening (NTS) based on high resolution …

CFM-ID 3.0: significantly improved ESI-MS/MS prediction and compound identification

Y Djoumbou-Feunang, A Pon, N Karu, J Zheng, C Li… - Metabolites, 2019 - mdpi.com
Metabolite identification for untargeted metabolomics is often hampered by the lack of
experimentally collected reference spectra from tandem mass spectrometry (MS/MS). To …

Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies

MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Advances in mass spectrometry based single-cell metabolomics

KD Duncan, J Fyrestam, I Lanekoff - Analyst, 2019 - pubs.rsc.org
Metabolomics has grown into a prominent field contributing to the molecular understanding
of complex biological processes in both health and disease. Furthermore, single-cells are …

Accelerating metabolite identification in natural product research: toward an ideal combination of liquid chromatography–high-resolution tandem mass spectrometry …

JL Wolfender, JM Nuzillard, JJJ Van Der Hooft… - Analytical …, 2018 - ACS Publications
Natural product research aims to characterize specialized metabolites from various living
organisms and assess their biological properties from either a chemical ecology or drug …

Advanced methods for natural products discovery: bioactivity screening, dereplication, metabolomics profiling, genomic sequencing, databases and informatic tools …

SP Gaudêncio, E Bayram, L Lukić Bilela, M Cueto… - Marine drugs, 2023 - mdpi.com
Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

Understanding glycaemic control and current approaches for screening antidiabetic natural products from evidence-based medicinal plants

C Lankatillake, T Huynh, DA Dias - Plant Methods, 2019 - Springer
Abstract Type 2 Diabetes Mellitus has reached epidemic proportions as a result of over-
nutrition and increasingly sedentary lifestyles. Current therapies, although effective, are not …