Fracture nonunion, a serious bone fracture complication, remains a challenge in clinical
practice. Although the molecular pathogenesis of nonunion remains unclear, a better …

Purpose Nonunion of fractures occurs in about 15% of all fractures causing repeated
surgical interference and prolonged morbidity. We performed this systematic review to …

Nonunion is a clinically significant complication of fracture associated with worse outcomes,
including increased pain, disability, and higher healthcare costs. The risk for nonunion is …

Compromised vascular supply and insufficient neovascularization impede bone repair,
increasing risk of non-union. Cyr61, Cysteine-rich angiogenic inducer of 61kD (also known …

Abstract Approximately 10–15% of fracture patients suffer impaired healing, which is either
delayed or even results in non-union. We performed a Systematic Review, aiming to …

High-altitude hypoxic environment exposure is considered one of the risk factors for
congenital heart disease (CHD), but the genetic factors involved are still unclear. CCN1, one …

Fracture non-union is the most challenging complication following fracture injuries. Despite
ongoing improvements in the surgical technique and implant design, the treatment efficacy …

Fracture non-union, prosthetic joint infection and fracture-related infections are
complications frequently encountered by the trauma and orthopaedic surgeon. Moreover …

Background Angiogenesis is a prerequisite for fracture repair, whereas insufficient blood
supply is likely to result in impaired healing. In the present study, we aimed to determine the …

Περίληψη Η πώρωση των καταγµάτων είναι ένα µείζων ζήτηµα που απασχολεί ειδικούς σε
παγκόσµιο επίπεδο, κυρίως λόγω των επιπλοκών που µπορούν να προκύψουν στην εξέλιξη …