Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

The future of ancient DNA: technical advances and conceptual shifts

M Hofreiter, JLA Paijmans, H Goodchild… - …, 2015 - Wiley Online Library
Technological innovations such as next generation sequencing and DNA hybridisation
enrichment have resulted in multi‐fold increases in both the quantity of ancient DNA …

Genomic structure in Europeans dating back at least 36,200 years

A Seguin-Orlando, TS Korneliussen, M Sikora… - Science, 2014 - science.org
The origin of contemporary Europeans remains contentious. We obtained a genome
sequence from Kostenki 14 in European Russia dating from 38,700 to 36,200 years ago …

Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle

SDE Park, DA Magee, PA McGettigan, MD Teasdale… - Genome biology, 2015 - Springer
Background Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the
two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic …

Reconstructing ancient genomes and epigenomes

L Orlando, MTP Gilbert, E Willerslev - Nature Reviews Genetics, 2015 - nature.com
Research involving ancient DNA (aDNA) has experienced a true technological revolution in
recent years through advances in the recovery of aDNA and, particularly, through …

Comparative performance of the BGISEQ-500 vs Illumina HiSeq2500 sequencing platforms for palaeogenomic sequencing

SST Mak, S Gopalakrishnan, C Carøe, C Geng… - …, 2017 - academic.oup.com
Ancient DNA research has been revolutionized following development of next-generation
sequencing platforms. Although a number of such platforms have been applied to ancient …

Comparing the performance of three ancient DNA extraction methods for high‐throughput sequencing

C Gamba, K Hanghøj, C Gaunitz… - Molecular Ecology …, 2016 - Wiley Online Library
The DNA molecules that can be extracted from archaeological and palaeontological
remains are often degraded and massively contaminated with environmental microbial …

Small RNA-mediated DNA methylation during plant reproduction

HT Chow, RA Mosher - The Plant Cell, 2023 - academic.oup.com
Reproductive tissues are a rich source of small RNAs, including several classes of short
interfering (si) RNAs that are restricted to this stage of development. In addition to RNA …

The Global Museum: natural history collections and the future of evolutionary science and public education

FT Bakker, A Antonelli, JA Clarke, JA Cook… - PeerJ, 2020 - peerj.com
Natural history museums are unique spaces for interdisciplinary research and educational
innovation. Through extensive exhibits and public programming and by hosting rich …

A domestication history of dynamic adaptation and genomic deterioration in Sorghum

O Smith, WV Nicholson, L Kistler, E Mace, A Clapham… - Nature plants, 2019 - nature.com
The evolution of domesticated cereals was a complex interaction of shifting selection
pressures and repeated episodes of introgression. Genomes of archaeological crops have …