Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Recyclable/degradable materials via the insertion of labile/cleavable bonds using a comonomer approach

C Lefay, Y Guillaneuf - Progress in Polymer Science, 2023 - Elsevier
Polymers have many advantages such as low weight, low cost, and, importantly, stability
under thermal, chemical, and mechanical stress. This stability, on the other hand, leads to …

Cleavable comonomers for chemically recyclable polystyrene: a general approach to vinyl polymer circularity

GR Kiel, DJ Lundberg, E Prince… - Journal of the …, 2022 - ACS Publications
Many common polymers, especially vinyl polymers, are inherently difficult to chemically
recycle and are environmentally persistent. The introduction of low levels of cleavable …

Controlled-Radical Polymerization of α-Lipoic Acid: A General Route to Degradable Vinyl Copolymers

KR Albanese, PT Morris, J Read de Alaniz… - Journal of the …, 2023 - ACS Publications
Here, we present the synthesis and characterization of statistical and block copolymers
containing α-lipoic acid (LA) using reversible addition–fragmentation chain-transfer (RAFT) …

Photocatalytic direct decarboxylation of carboxylic acids to derivatize or degrade polymers

A Adili, AB Korpusik, D Seidel… - Angewandte Chemie …, 2022 - Wiley Online Library
Visible light‐mediated direct decarboxylation of carboxylic acids with an acridine
photocatalyst is a convenient and powerful method to generate carbon‐centered radicals in …

Degradation of polyacrylates by one-pot sequential dehydrodecarboxylation and ozonolysis

AB Korpusik, A Adili, K Bhatt, JE Anatot… - Journal of the …, 2023 - ACS Publications
We establish a synthetically convenient method to degrade polyacrylate homopolymers.
Carboxylic acids are installed along the polymer backbone by partial hydrolysis of the ester …

100th anniversary of macromolecular science viewpoint: Degradable polymers from radical ring-opening polymerization: Latest advances, new directions, and …

T Pesenti, J Nicolas - ACS Macro Letters, 2020 - ACS Publications
Radical ring-opening polymerization (rROP) allows facile incorporation of labile groups (eg,
ester) into the main chain of vinyl polymers to obtain (bio) degradable materials. rROP has …

Clip chemistry: diverse (bio)(macro) molecular and material function through breaking covalent bonds

P Shieh, MR Hill, W Zhang, SL Kristufek… - Chemical …, 2021 - ACS Publications
In the two decades since the introduction of the “click chemistry” concept, the toolbox of “click
reactions” has continually expanded, enabling chemists, materials scientists, and biologists …

Building tunable degradation into high-performance poly (acrylate) pressure-sensitive adhesives

KR Albanese, Y Okayama, PT Morris, M Gerst… - ACS Macro …, 2023 - ACS Publications
Pressure-sensitive adhesives (PSAs) based on poly (acrylate) chemistry are common in a
wide variety of applications, but the absence of backbone degradability causes issues with …

Degradable polymers via olefin metathesis polymerization

H Sun, Y Liang, MP Thompson… - Progress in polymer …, 2021 - Elsevier
The development of degradable polymers has commanded significant attention over the
past half century. Approaches have predominantly relied on ring-opening polymerization of …