50+ years of eukaryotic transcription: an expanding universe of factors and mechanisms
RG Roeder - Nature structural & molecular biology, 2019 - nature.com
The landmark 1969 discovery of nuclear RNA polymerases I, II and III in diverse eukaryotes
represented a major turning point in the field that, with subsequent elucidation of the distinct …
represented a major turning point in the field that, with subsequent elucidation of the distinct …
Acetylation of histones and transcription-related factors
DE Sterner, SL Berger - Microbiology and molecular biology …, 2000 - Am Soc Microbiol
The state of chromatin (the packaging of DNA in eukaryotes) has long been recognized to
have major effects on levels of gene expression, and numerous chromatin-altering …
have major effects on levels of gene expression, and numerous chromatin-altering …
Repetitive zinc‐binding domains in the protein transcription factor IIIA from Xenopus oocytes.
The 7S particle of Xenopus laevis oocytes contains 5S RNA and a 40‐K protein which is
required for 5S RNA transcription in vitro. Proteolytic digestion of the protein in the particle …
required for 5S RNA transcription in vitro. Proteolytic digestion of the protein in the particle …
Plasticity of the differentiated state
Heterokaryons provide a model system in which to examine how tissue-specific phenotypes
arise and are maintained. When muscle cells are fused with nonmuscle cells, muscle gene …
arise and are maintained. When muscle cells are fused with nonmuscle cells, muscle gene …
Recruitment of RNA polymerase III to its target promoters
L Schramm, N Hernandez - Genes & development, 2002 - genesdev.cshlp.org
A key step in retrieving the information stored in the complex genomes of eukaryotes
involves the identification of transcription units and, more specifically, the recognition of …
involves the identification of transcription units and, more specifically, the recognition of …
A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization
VP Sukhatme, X Cao, LC Chang, CH Tsai-Morris… - Cell, 1988 - cell.com
Egr-7 is an early growth response gene that displays fos-like induction kinetics in fibroblasts,
epithelial cells, and lymphocytes following mitogenic stimulation. Sequence analysis of …
epithelial cells, and lymphocytes following mitogenic stimulation. Sequence analysis of …
Survey and summary transcription by RNA polymerases I and III
MR Paule, RJ White - Nucleic acids research, 2000 - academic.oup.com
The task of transcribing nuclear genes is shared between three RNA polymerases in
eukaryotes: RNA polymerase (pol) I synthesises the large rRNA, pol II synthesises mRNA …
eukaryotes: RNA polymerase (pol) I synthesises the large rRNA, pol II synthesises mRNA …
Transfer RNAs: diversity in form and function
As the adaptor that decodes mRNA sequence into protein, the basic aspects of tRNA
structure and function are central to all studies of biology. Yet the complexities of their …
structure and function are central to all studies of biology. Yet the complexities of their …
A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly
B Ruskin, PD Zamore, MR Green - Cell, 1988 - cell.com
Pre-mRNA splicing complex assembly is mediated by two specific pre-mRNA-snRNP
interactions: Ul snRNP binds to the 5'splice site and U2 snRNP binds to the branch point …
interactions: Ul snRNP binds to the 5'splice site and U2 snRNP binds to the branch point …
[HTML][HTML] Transcriptional regulation and the role of diverse coactivators in animal cells
RG Roeder - FEBS letters, 2005 - Elsevier
Transcriptional regulation in eukaryotes involves structurally and functionally distinct nuclear
RNA polymerases, corresponding general initiation factors, gene-specific (DNA-binding) …
RNA polymerases, corresponding general initiation factors, gene-specific (DNA-binding) …