Cocrystals are an emerging class of crystalline materials composed of two or more different
molecules in the same crystal lattice that are physically connected by non-ionic and non …

Mechanochemistry is considered an alternative attractive greener approach to prepare
diverse molecular compounds and has become an important synthetic tool in different fields …

Recently, the application of mechanochemical strategies in organic synthesis has attracted
the attention of both the academic and industrial chemical communities. The high efficiency …

Introduction Infections caused by parasitic flatworms impose a considerable worldwide
health burden. Recently, World Health Organization launched its roadmap for neglected …

Chiral compounds that crystallize as conglomerates from racemic mixtures are desirable
from the perspective of chiral resolution since they are relatively easy to resolve using, for …

Sildenafil is a drug used to treat erectile dysfunction and pulmonary arterial hypertension.
Because of poor aqueous solubility of the drug, the citrate salt, with improved solubility and …

Investigations on praziquantel (PZQ) started fifty years ago by a cooperation between Bayer
AG and Merck KGaA. Until today PZQ is the drug of choice for schistosomiasis in human …

Non-covalent derivatives (NCDs) are formed by incorporating one (or more) coformer
molecule (s) into the matrix of a parent molecule via non-covalent forces. These forces can …

Pharmaceutical cocrystals are highly interesting due to their effect on physicochemical
properties and their role in separation technologies, particularly for chiral molecules …

The purpose is to study the dissolution behaviour for praziquantel in different solvent. The
dissolution capacity within the temperature range from 273.15 K to 313.15 K was researched …