Epithelial cells are the most common cell type in all animals, forming the sheets and tubes
that compose most organs and tissues. Apical–basal polarity is essential for epithelial cell …

The basement membrane (BM) is a thin, planar-organized extracellular matrix that underlies
epithelia and surrounds most organs. During development, the BM is highly dynamic and …

Neuronal autophagosomes form and engulf cargos at presynaptic sites in the axon and are
then transported to the soma to recycle their cargo. Autophagic vacuoles (AVs) mature en …

The interactions between cells and their surrounding extracellular matrix (ECM) are dynamic
and play critical roles in cell migration during development, health, and diseases. Recent …

Cell-extracellular matrix interactions have been studied extensively using cells cultured in
vitro. These studies indicate that focal adhesion (FA)-based cell-extracellular matrix …

Caenorhabditis elegans neurons under stress can produce giant vesicles, several microns
in diameter, called exophers. Current models suggest that exophers are neuroprotective …

Silica-induced lung epithelial injury and fibrosis are vital pathogeneses of silicosis. Although
the NOD-like receptor protein 3 (NLRP3) inflammasome contributes to silica-induced …

Extracellular matrices contain fibril-like polymers often organized in parallel arrays. Although
their role in morphogenesis has been long recognized, it remains unclear how the …

Gamete development is a fundamental process that is highly conserved from early
eukaryotes to mammals. As germ cells develop, they must coordinate a dynamic series of …

In many species, only one oocyte is specified among a group of interconnected germline
sister cells. In Drosophila melanogaster, 16 interconnected cells form a germline cyst, where …