[HTML][HTML] miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
miRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets
CM Klinge - Molecular and cellular endocrinology, 2015 - Elsevier
Abstract MicroRNAs (miRNAs) are short (22 nucleotides), single-stranded, non-coding
RNAs that form complimentary base-pairs with the 3′ untranslated region of target mRNAs …
RNAs that form complimentary base-pairs with the 3′ untranslated region of target mRNAs …
A Molecular Portrait of High-Grade Ductal Carcinoma In Situ
Ductal carcinoma in situ (DCIS) is a noninvasive precursor lesion to invasive breast
carcinoma. We still have no understanding on why only some DCIS lesions evolve to …
carcinoma. We still have no understanding on why only some DCIS lesions evolve to …
[HTML][HTML] Refinement of breast cancer molecular classification by miRNA expression profiles
R Søkilde, H Persson, A Ehinger, AC Pirona, M Fernö… - BMC genomics, 2019 - Springer
Background Accurate classification of breast cancer using gene expression profiles has
contributed to a better understanding of the biological mechanisms behind the disease and …
contributed to a better understanding of the biological mechanisms behind the disease and …
[HTML][HTML] MicroRNAs in molecular classification and pathogenesis of breast tumors
Simple Summary Breast cancer is an ideal model of a heterogeneous disease that is
triggered by genetic changes in the normal mammary epithelial cells and manifest as …
triggered by genetic changes in the normal mammary epithelial cells and manifest as …
[HTML][HTML] Non-coding RNAs modulating estrogen signaling and response to endocrine therapy in breast cancer
O Treeck, S Haerteis, O Ortmann - Cancers, 2023 - mdpi.com
Simple Summary Endocrine therapy is a common treatment for estrogen-responsive breast
cancer, which is used to block the tumor growth-promoting effect of this hormone. The …
cancer, which is used to block the tumor growth-promoting effect of this hormone. The …
[HTML][HTML] Breast cancer subtype-specific mirnas: networks, impacts, and the potential for intervention
The regulatory and functional roles of non-coding RNAs are increasingly demonstrated as
critical in cancer. Among non-coding RNAs, microRNAs (miRNAs) are the most well-studied …
critical in cancer. Among non-coding RNAs, microRNAs (miRNAs) are the most well-studied …
[HTML][HTML] The role of MicroRNAs in HER2-Positive breast Cancer: where we are and future prospective
V Fogazzi, M Kapahnke, A Cataldo, I Plantamura… - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is the most diagnosed malignancy in woman worldwide
and, despite the availability of new innovative therapies, it remains the first cause of death …
and, despite the availability of new innovative therapies, it remains the first cause of death …
[HTML][HTML] The role of different types of microRNA in the pathogenesis of breast and prostate cancer
EA Sidorova, YV Zhernov, MA Antsupova… - International Journal of …, 2023 - mdpi.com
Micro ribonucleic acids (microRNAs or miRNAs) form a distinct subtype of non-coding RNA
and are widely recognized as one of the most significant gene expression regulators in …
and are widely recognized as one of the most significant gene expression regulators in …
Passenger strand loading in overexpression experiments using microRNA mimics
MicroRNAs (miRNAs) are important regulators of gene function and manipulation of miRNAs
is a central component of basic research. Modulation of gene expression by miRNA gain-of …
is a central component of basic research. Modulation of gene expression by miRNA gain-of …