Gene delivery has revolutionized conventional medical approaches to vaccination, cancer,
and autoimmune diseases. However, current gene delivery methods are limited to either …

DNA‐based materials have attracted interest due to the tunable structure and encoded
biological functionality of nucleic acids. A simple and general approach to synthesize DNA …

RNA biology has gained extensive recognition in the last two decades due to the
identification of novel transcriptomic elements and molecular functions. Cancer arises, in …

Several recent attempts to improve the stability and immunogenicity of messenger RNA
(mRNA) vaccines include the use of circular RNA (circRNA), targeted delivery, and …

In light of the recent pandemic, several COVID-19 vaccines were developed, tested and
approved in a very short time, a process that otherwise takes many years. Above all, these …

Dear Editor, mRNA vaccines are advantageous for Africa. They could potentially be utilized
against other African viral and bacterial diseases other than COVID-19 [1]. They are highly …

Amphiphilic Janus dendrimers (JDs), synthetic alternatives to lipids, have the potential to
expand the scope of nanocarrier delivery systems. JDs self-assemble into vesicles called …

In vaccine development, many use the spike protein (S protein), which has multiple “spike-
like” structures protruding from the spherical structure of the coronavirus, as an antigen …

Programmable lipid nanoparticles (LNPs) offer precise spatiotemporal control over drug
distribution and release, a critical advancement for treating complex diseases like cancer …