Genetics and molecular biology of rhythms in Drosophila and other insects

JC Hall - 2003 - Elsevier
Application of genetic variants (Sections II–IV, VI, and IX) and molecular manipulations of
rhythm-related genes (Sections V–X) have been used experimentally to investigate features …

Genetic and molecular analysis of circadian rhythms

JC Dunlap - Annual review of genetics, 1996 - annualreviews.org
▪ Abstract The first part of this review summarizes the two best understood aspects of the two
best understood circadian systems, the feedback oscillators of Neurospora and Drosophila …

Natural Variation in a Drosophila Clock Gene and Temperature Compensation

LA Sawyer, JM Hennessy, AA Peixoto, E Rosato… - Science, 1997 - science.org
The threonine-glycine (Thr-Gly) encoding repeat within the clock gene period of Drosophila
melanogaster is polymorphic in length. The two major variants (Thr-Gly) 17 and (Thr-Gly) 20 …

Climatic selection on genes and traits after a 100 year-old invasion: a critical look at the temperate-tropical clines in Drosophila melanogaster from eastern Australia

AA Hoffmann, AR Weeks - Genetica, 2007 - Springer
Drosophila melanogaster invaded Australia around 100 years ago, most likely through a
northern invasion. The wide range of climatic conditions in eastern Australia across which D …

Clines in clock genes: fine-tuning circadian rhythms to the environment

CP Kyriacou, AA Peixoto, F Sandrelli, R Costa… - Trends in Genetics, 2008 - cell.com
The dissection of the circadian clock into its molecular components represents the most
striking and well-studied example of a gene regulatory network underlying a complex …

A latitudinal cline in the Chinook salmon (Oncorhynchus tshawytscha) Clock gene: evidence for selection on PolyQ length variants

KG O'Malley, MA Banks - Proceedings of the Royal …, 2008 - royalsocietypublishing.org
A critical seasonal event for anadromous Chinook salmon (Oncorhynchus tshawytscha) is
the time at which adults migrate from the ocean to breed in freshwater. We investigated …

Timeless in animal circadian clocks and beyond

YD Cai, JC Chiu - The FEBS journal, 2022 - Wiley Online Library
TIMELESS (TIM) was first identified as a molecular cog in the Drosophila circadian clock.
Almost three decades of investigations have resulted in an insightful model describing the …

The period Gene Thr-Gly Polymorphism in Australian and African Drosophila melanogaster Populations: Implications for Selection

LA Sawyer, F Sandrelli, C Pasetto, AA Peixoto… - Genetics, 2006 - academic.oup.com
The period gene is a key regulator of biological rhythmicity in Drosophila melanogaster. The
central part of the gene encodes a dipeptide Thr-Gly repeat that has been implicated in the …

Circadian clocks: what makes them tick?

M Zordan, R Costa, G Macino… - Chronobiology …, 2000 - Taylor & Francis
In the not too distant past, it was common belief that rhythms in the physical environment
were the driving force, to which organisms responded passively, for the observed daily …

Molecular coevolution within a Drosophila clock gene

AA Peixoto, JM Hennessy, I Townson… - Proceedings of the …, 1998 - National Acad Sciences
The period (per) gene in Drosophila melanogaster provides an integral component of
biological rhythmicity and encodes a protein that includes a repetitive threonine-glycine (Thr …