Micro total analysis systems: fundamental advances and applications

DEW Patabadige, S Jia, J Sibbitts, J Sadeghi… - Analytical …, 2016 - ACS Publications
It has been 14 years since the inaugural microfluidics review in Analytical Chemistry was
published. 1 The first papers describing these devices which are also commonly referred to …

In-plane plasmonic antenna arrays with surface nanogaps for giant fluorescence enhancement

V Flauraud, R Regmi, PM Winkler, DTL Alexander… - Nano …, 2017 - ACS Publications
Optical nanoantennas have a great potential for enhancing light-matter interactions at the
nanometer scale, yet fabrication accuracy and lack of scalability currently limit ultimate …

Self-assembled nanoparticle dimer antennas for plasmonic-enhanced single-molecule fluorescence detection at micromolar concentrations

D Punj, R Regmi, A Devilez, R Plauchu… - ACS …, 2015 - ACS Publications
Plasmonic antennas offer extremely promising strategies to enhance single molecule
fluorescence sensing and breach the limitations set by diffraction. However, the technical …

Roadmap on biosensing and photonics with advanced nano-optical methods

E Di Fabrizio, S Schlücker, J Wenger, R Regmi… - Journal of …, 2016 - iopscience.iop.org
This roadmap, through the contributions of ten groups worldwide, contains different
techniques, methods and materials devoted to sensing in nanomedicine. Optics is used in …

Nano-spectroscopic imaging of proteins with near-field scanning optical microscopy (NSOM)

YC Yong, YZ Wang, JJ Zhong - Current opinion in biotechnology, 2018 - Elsevier
Highlights•Near-field scanning optical microscopy (NSOM) is promising for protein
nanoimaging.•Spectroscopic NSOM opens up the possibility for single protein …

Chiral metamaterials via Moiré stacking

Z Wu, Y Liu, EH Hill, Y Zheng - Nanoscale, 2018 - pubs.rsc.org
Chiral metamaterials have attracted strong interest due to their versatile capabilities in spin-
dependent light manipulation. Benefiting from advancements in nanofabrication and …

Planar optical nanoantennas resolve cholesterol-dependent nanoscale heterogeneities in the plasma membrane of living cells

R Regmi, PM Winkler, V Flauraud, KJE Borgman… - Nano …, 2017 - ACS Publications
Optical nanoantennas can efficiently confine light into nanoscopic hotspots, enabling single-
molecule detection sensitivity at biological relevant conditions. This innovative approach to …

Nanoscale volume confinement and fluorescence enhancement with double nanohole aperture

R Regmi, AA Al Balushi, H Rigneault, R Gordon… - Scientific reports, 2015 - nature.com
Diffraction ultimately limits the fluorescence collected from a single molecule and sets an
upper limit to the maximum concentration to isolate a single molecule in the detection …

Optical antenna-based fluorescence correlation spectroscopy to probe the nanoscale dynamics of biological membranes

PM Winkler, R Regmi, V Flauraud… - The journal of …, 2018 - ACS Publications
The plasma membrane of living cells is compartmentalized at multiple spatial scales ranging
from the nano-to the mesoscale. This nonrandom organization is crucial for a large number …

Hybrid plasmonic nanostructures for enhanced single-molecule detection sensitivity

EK Herkert, DR Bermeo Alvaro, M Recchia… - ACS …, 2023 - ACS Publications
Biosensing applications based on fluorescence detection often require single-molecule
sensitivity in the presence of strong background signals. Plasmonic nanoantennas are …