Aptamers are nucleic acids referred to as chemical antibodies as they bind to their specific
targets with high affinity and selectivity. They are selected via an iterative process known as …

A key goal of modern medicine is target‐specific therapeutic intervention. However, most
drugs lack selectivity, resulting in 'off‐target'side effects. To address the requirements of …

Conspectus Fluorescence bioimaging in the second near-infrared window (NIR-II, 1000–
1700 nm) is a superior visualization tool with deeper penetration and higher spatial …

High levels of heat shock protein 70 (HSP70) in tumors are commonly associated with poor
prognosis, enhanced doxorubicin (DOX)-induced cardiotoxicity, and even drug resistance in …

Biomimetic binders and catalysts have been generated in order to substitute the biological
pendants in separation techniques and bioanalysis. The two major approaches use either …

Purpose To construct and test a hepatocellular carcinoma (HCC)-targeted magnetic
resonance probe based on a glypican-3 (GPC3)-specific aptamer (AP613-1) with ultrasmall …

Aptamers are oligonucleotide molecules able to recognize very specifically proteins. Among
the possible applications, aptamers have been used for affinity chromatography with …

Featured Application The aptamer-functionalized DNA hydrogel will be a good candidate for
controlled protein delivery. Abstract With the simple functionalization method and good …

Aptamers are widely used as diagnostic agents due to their specificity and high binding
affinity to their cognate target. Apart from diagnostic applications, aptamers can also be …

Spiegelmers are enantiomers of natural D-oligonucleotides that bind to targets with distinct
structures such as aptamers. The high susceptibility of natural D-form aptamers to nucleases …