Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases
The human intestine hosts diverse microbial communities that play a significant role in
maintaining gut-skin homeostasis. When the relationship between gut microbiome and the …
maintaining gut-skin homeostasis. When the relationship between gut microbiome and the …
Hidradenitis suppurativa
R Sabat, GBE Jemec, Ł Matusiak, AB Kimball… - Nature Reviews …, 2020 - nature.com
Hidradenitis suppurativa (HS; also designated as acne inversa) is a chronic inflammatory
disorder, which affects the intertriginous skin and is associated with numerous systemic …
disorder, which affects the intertriginous skin and is associated with numerous systemic …
Secukinumab in moderate-to-severe hidradenitis suppurativa (SUNSHINE and SUNRISE): week 16 and week 52 results of two identical, multicentre, randomised …
Background Few therapeutic options are available for patients with moderate-to-severe
hidradenitis suppurativa. We aimed to assess the efficacy of secukinumab in patients with …
hidradenitis suppurativa. We aimed to assess the efficacy of secukinumab in patients with …
The IL-23/IL-17 pathway in inflammatory skin diseases: from bench to bedside
T Liu, S Li, S Ying, S Tang, Y Ding, Y Li, J Qiao… - Frontiers in …, 2020 - frontiersin.org
Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by
the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells. IL-17A is …
the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells. IL-17A is …
Hidradenitis suppurativa: advances in diagnosis and treatment
DML Saunte, GBE Jemec - Jama, 2017 - jamanetwork.com
Importance Hidradenitis suppurativa (HS) is relatively common, with the prevalence of
0.05% to 4.10%, yet many patients receive inadequate treatment. Objective To review the …
0.05% to 4.10%, yet many patients receive inadequate treatment. Objective To review the …
Aetiology and pathogenesis of hidradenitis suppurativa
K Wolk, O Join‐Lambert, R Sabat - British Journal of …, 2020 - academic.oup.com
Hidradenitis suppurativa (HS) is a chronic inflammatory disorder. Patients develop inflamed
nodules and abscesses and, at later stages of disease, epithelialized tunnels and scars in …
nodules and abscesses and, at later stages of disease, epithelialized tunnels and scars in …
What causes hidradenitis suppurativa?—15 years after
CC Zouboulis, F Benhadou, AS Byrd… - Experimental …, 2020 - Wiley Online Library
The 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis
published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International …
published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International …
Evaluating patients' unmet needs in hidradenitis suppurativa: Results from the Global Survey Of Impact and Healthcare Needs (VOICE) Project
Background A needs assessment for patients with hidradenitis suppurativa (HS) will support
advancements in multidisciplinary care, treatment, research, advocacy, and philanthropy …
advancements in multidisciplinary care, treatment, research, advocacy, and philanthropy …
Hidradenitis suppurativa: a systematic review integrating inflammatory pathways into a cohesive pathogenic model
ARJV Vossen, HH Van der Zee, EP Prens - Frontiers in immunology, 2018 - frontiersin.org
Background: The pathogenesis of hidradenitis suppurativa (HS) is not fully understood. This
systematic review examined the latest evidence for molecular inflammatory pathways …
systematic review examined the latest evidence for molecular inflammatory pathways …
Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease
Cell death is a vital process that occurs in billions of cells in the human body every day. This
process helps maintain tissue homeostasis, supports recovery from acute injury, deals with …
process helps maintain tissue homeostasis, supports recovery from acute injury, deals with …