DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …

New non-invasive approaches that can complement and improve on current strategies for
colorectal cancer (CRC) screening and management are urgently needed. A growing …

Cell lines are invaluable biomedical research tools, and recent literature has emphasized
the importance of genotype authentication and characterization. In the present study, 24 out …

Background The development of colorectal cancer (CRC) is accompanied by extensive
epigenetic changes, including frequent regional hypermethylation particularly of gene …

Background Given the differences in embryonic origin, vascular and nervous supplies,
microbiotic burden, and main physiological functions of left and right colons, tumor location …

Transforming growth factor-β (TGF-β) is an intriguing cytokine exhibiting dual activities in
malignant disease. It is an important mediator of cancer invasion, metastasis and …

Extracellular matrix (ECM) remodeling is crucial in the regulation of gastric cancer (GC)
progression. This work aims to reveal novel posttranslational modifications and their …

Colorectal cancer (CRC) is among the most common cancers. In fact, it is placed in the third
place among the most diagnosed cancer in men, after lung and prostate cancer, and in the …

Colorectal cancer (CRC) is associated with significant morbidity and mortality in the US and
worldwide. CRC is the second most common cancer‐related death in both men and women …

The sex ratio is a key ecological demographic parameter crucial for population viability.
However, the epigenetic mechanisms operating during gonadal development regulating …