Inteins are mobile genetic elements that apply standard enzymatic strategies to excise
themselves post-translationally from the precursor protein via protein splicing. Since their …

Background Lignocellulosic biomass is considered as a promising alternative to fossil
resources for the production of fuels, materials and chemicals. Efficient enzymatic systems …

Multidrug-resistant pathogens are of significant concern in recent years. Hence new
antifungal and anti-bacterial drug targets are urgently needed before the situation goes …

Self splicing introns and inteins that rely on a homing endonuclease for propagation are
parasitic genetic elements. Their life-cycle and evolutionary fate has been described through …

Background Members of the small multidrug resistance (SMR) protein family are integral
membrane proteins characterized by four α-helical transmembrane strands that confer …

Inteins, also called protein introns, are self-splicing mobile elements found in all domains of
life. A bioinformatic survey of genomic data highlights a biased distribution of inteins among …

The spliceosome is a large ribonucleoprotein complex that removes introns from pre-
mRNAs. At its functional core lies the essential pre-mRNA processing factor 8 (Prp8) protein …

Protein splicing is a post-translational process by which an intervening polypeptide, or
intein, catalyzes its own removal from the flanking polypeptides, or exteins, concomitant with …

The judicious application of intein technologies to biological problems has resulted in
powerful tools for biomedical research. Inteins are intervening sequences that excise …

A recent species status investigation of the pathogenic fungus Paracoccidioides brasiliensis
suggested the existence of three cryptic species. In the present study, the sequences of the …