Synapses are specialized junctions between neurons in brain that transmit and compute
information, thereby connecting neurons into millions of overlapping and interdigitated …

Genetics studies of autism spectrum disorder (ASD) have identified several risk genes that
are key regulators of synaptic plasticity. Indeed, many of the risk genes that have been …

Autism Spectrum Disorders (ASD) and Schizophrenia (SCZ) are cognitive disorders with
complex genetic architectures but overlapping behavioral phenotypes, which suggests …

The brain processes information by transmitting signals at synapses, which connect neurons
into vast networks of communicating cells. In these networks, synapses not only transmit …

Neurexins are evolutionarily conserved presynaptic cell-adhesion molecules that are
essential for normal synapse formation and synaptic transmission. Indirect evidence has …

Elucidation of molecular mechanisms that regulate synapse formation is required for the
understanding of neural wiring, higher brain functions, and mental disorders. Despite the …

In the mammalian CNS, each neuron typically receives thousands of synaptic inputs from
diverse classes of neurons. Synaptic transmission to the postsynaptic neuron relies on …

Neurexins are essential presynaptic cell adhesion molecules that are linked to
schizophrenia and autism and are subject to extensive alternative splicing. Here, we used a …

Synaptic adhesion molecules are thought to play a critical role in the formation, function and
plasticity of neuronal networks. Neuroligins (NL1–4) are a family of presumptive …

AMPA-and NMDA-type glutamate receptors mediate distinct postsynaptic signals that differ
characteristically among synapses. How postsynaptic AMPA-and NMDA-receptor levels are …