MicroRNA-155: a master regulator of inflammation
MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (∼ 22
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …
MicroRNAs in development and disease
D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …
introduced an additional level of intricacy to our understanding of gene regulation. There are …
Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyperexpression of interleukin-8
S Bhattacharyya, NS Balakathiresan, C Dalgard… - Journal of Biological …, 2011 - ASBMB
Cystic Fibrosis (CF) is characterized by a massive proinflammatory phenotype in the lung
arising from profound expression of inflammatory genes, including interleukin-8 (IL-8). We …
arising from profound expression of inflammatory genes, including interleukin-8 (IL-8). We …
MicroRNomics: a newly emerging approach for disease biology
C Zhang - Physiological genomics, 2008 - journals.physiology.org
Genomic evidence reveals that gene expression in humans is precisely controlled in
cellular, tissue-type, temporal, and condition-specific manners. Completely understanding …
cellular, tissue-type, temporal, and condition-specific manners. Completely understanding …
MicroRNAs in control of cardiac hypertrophy
PA Da Costa Martins, LJ De Windt - Cardiovascular research, 2012 - academic.oup.com
MicroRNAs refer to a subfamily of small non-coding RNA species that are designed to
influence gene expression in nearly all cell types studied to date. Studies from the past …
influence gene expression in nearly all cell types studied to date. Studies from the past …
Differential expression of microRNAs in different disease states
M Abdellatif - Circulation research, 2012 - Am Heart Assoc
Disturbances in gene expression as a result of perturbed transcription or posttranscriptional
regulation is one of the main causes of cellular dysfunction that underlies different disease …
regulation is one of the main causes of cellular dysfunction that underlies different disease …
MicroRNAs in the cardiovascular system
M Han, J Toli, M Abdellatif - Current opinion in cardiology, 2011 - journals.lww.com
MicroRNAs in the cardiovascular system : Current Opinion in Cardiology MicroRNAs in the
cardiovascular system : Current Opinion in Cardiology Log in or Register Subscribe to …
cardiovascular system : Current Opinion in Cardiology Log in or Register Subscribe to …
Identification of a novel risk locus for multiple sclerosis at 13q31. 3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms
M Comabella, DW Craig, M Camina-Tato, C Morcillo… - PloS one, 2008 - journals.plos.org
Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous
system with an important genetic component and strongest association driven by the HLA …
system with an important genetic component and strongest association driven by the HLA …
GATA4 expression is primarily regulated via a miR-26b-dependent post-transcriptional mechanism during cardiac hypertrophy
M Han, Z Yang, D Sayed, M He, S Gao… - Cardiovascular …, 2012 - academic.oup.com
Aims GATA4 is a transcription factor that is up-regulated during cardiac hypertrophy and
plays a fundamental role in myocyte growth and survival. In this study, we investigate the …
plays a fundamental role in myocyte growth and survival. In this study, we investigate the …
Stem cell-based delivery of Hypoxamir-210 to the infarcted heart: implications on stem cell survival and preservation of infarcted heart function
This study seeks to test our hypothesis that transgenic induction of miR-210 in mesenchymal
stem cells (MSC) simulates the pro-survival effects of ischemic preconditioning (IPC) and …
stem cells (MSC) simulates the pro-survival effects of ischemic preconditioning (IPC) and …