MicroRNA-155: a master regulator of inflammation

G Mahesh, R Biswas - Journal of Interferon & Cytokine Research, 2019 - liebertpub.com
MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (∼ 22
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyperexpression of interleukin-8

S Bhattacharyya, NS Balakathiresan, C Dalgard… - Journal of Biological …, 2011 - ASBMB
Cystic Fibrosis (CF) is characterized by a massive proinflammatory phenotype in the lung
arising from profound expression of inflammatory genes, including interleukin-8 (IL-8). We …

MicroRNomics: a newly emerging approach for disease biology

C Zhang - Physiological genomics, 2008 - journals.physiology.org
Genomic evidence reveals that gene expression in humans is precisely controlled in
cellular, tissue-type, temporal, and condition-specific manners. Completely understanding …

MicroRNAs in control of cardiac hypertrophy

PA Da Costa Martins, LJ De Windt - Cardiovascular research, 2012 - academic.oup.com
MicroRNAs refer to a subfamily of small non-coding RNA species that are designed to
influence gene expression in nearly all cell types studied to date. Studies from the past …

Differential expression of microRNAs in different disease states

M Abdellatif - Circulation research, 2012 - Am Heart Assoc
Disturbances in gene expression as a result of perturbed transcription or posttranscriptional
regulation is one of the main causes of cellular dysfunction that underlies different disease …

MicroRNAs in the cardiovascular system

M Han, J Toli, M Abdellatif - Current opinion in cardiology, 2011 - journals.lww.com
MicroRNAs in the cardiovascular system : Current Opinion in Cardiology MicroRNAs in the
cardiovascular system : Current Opinion in Cardiology Log in or Register Subscribe to …

Identification of a novel risk locus for multiple sclerosis at 13q31. 3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms

M Comabella, DW Craig, M Camina-Tato, C Morcillo… - PloS one, 2008 - journals.plos.org
Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous
system with an important genetic component and strongest association driven by the HLA …

GATA4 expression is primarily regulated via a miR-26b-dependent post-transcriptional mechanism during cardiac hypertrophy

M Han, Z Yang, D Sayed, M He, S Gao… - Cardiovascular …, 2012 - academic.oup.com
Aims GATA4 is a transcription factor that is up-regulated during cardiac hypertrophy and
plays a fundamental role in myocyte growth and survival. In this study, we investigate the …

Stem cell-based delivery of Hypoxamir-210 to the infarcted heart: implications on stem cell survival and preservation of infarcted heart function

HW Kim, S Jiang, M Ashraf, KH Haider - Journal of Molecular Medicine, 2012 - Springer
This study seeks to test our hypothesis that transgenic induction of miR-210 in mesenchymal
stem cells (MSC) simulates the pro-survival effects of ischemic preconditioning (IPC) and …