Transporters influence the disposition of chemicals within the body by participating in
absorption, distribution, and elimination. Transporters of the solute carrier family (SLC) …

1. The peptide transporters belong to the peptide transporter (PTR) family and serve as
integral membrane proteins for the cellular uptake of di-and tripeptides in the organism. By …

Carrier-mediated transporters play a critical role in xenobiotic disposition and transporter
research is complicated by species differences and their selective tissue expression. The …

The role of transporters in drug absorption, distribution and elimination processes as well as
in drug–drug interactions is increasingly being recognised. Although the lungs express high …

Uptake of nutrients into cells is essential to life and occurs in all organisms at the expense of
energy. Whereas in most prokaryotic and simple eukaryotic cells electrochemical …

The liver is essential for survival due to its critical role in the regulation of metabolic
homeostasis. Metabolism of xenobiotics, such as environmental chemicals and drugs by the …

Optical control of protein function provides excellent spatial-temporal resolution for studying
proteins in situ. Although light-sensitive exogenous proteins and ligands have been used to …

Abstract Effect of pulsed electric field (PEF) on in-vitro simulated gastrointestinal protein
digestion of cold-boned beef Semimembranosus was elucidated. PEF treated [T 1, 5.0 kV …

Interest into the effects of carnosine on cellular metabolism is rapidly expanding. The first
study to demonstrate in humans that chronic β-alanine (BA) supplementation (~ 3–6 g …

Lysine is an essential amino acid that serves as a building block in protein synthesis. Beside
this, the metabolic activity of lysine has only recently been unraveled. Lysine metabolism is …