[HTML][HTML] Development of forced degradation and stability indicating studies of drugs—A review
M Blessy, RD Patel, PN Prajapati… - Journal of pharmaceutical …, 2014 - Elsevier
Forced degradation is a degradation of new drug substance and drug product at conditions
more severe than accelerated conditions. It is required to demonstrate specificity of stability …
more severe than accelerated conditions. It is required to demonstrate specificity of stability …
Application of PAT-based feedback control approaches in pharmaceutical crystallization
Crystallization is one of the important unit operations for the separation and purification of
solid products in the chemical, pharmaceutical, and pesticide industries, especially for …
solid products in the chemical, pharmaceutical, and pesticide industries, especially for …
Fast one-pot microwave-assisted green synthesis of highly fluorescent plant-inspired S, N-self-doped carbon quantum dots as a sensitive probe for the antiviral drug …
In this study, we report a one-pot, green, cost-efficient, and fast synthesis of plant-based
sulfur and nitrogen self-co-doped carbon quantum dots (S, N-CQDs). By 4-min microwave …
sulfur and nitrogen self-co-doped carbon quantum dots (S, N-CQDs). By 4-min microwave …
A specific turn-on fluorescence probe for determination of nitazoxanide based on feasible oxidation reaction with hypochlorite: Applying cobalt ferrite nanoparticles for …
Nitazoxanide is an antimicrobial compound that was originally developed as an
antiprotozoal drug. Recently nitazoxanide has been identified as broad-spectrum antiviral …
antiprotozoal drug. Recently nitazoxanide has been identified as broad-spectrum antiviral …
[PDF][PDF] Forced degradation studies
Forced degradation studies include the degradation of new drug substance and drug
product at conditions more severe than accelerated conditions. These studies illustrate the …
product at conditions more severe than accelerated conditions. These studies illustrate the …
Enhancing the solubility of nitazoxanide with solid dispersions technique: formulation, evaluation, and cytotoxicity study
S Sood, B Maddiboyina, P Rawat, AK Garg… - Journal of …, 2020 - Taylor & Francis
Nitazoxanide (NTZ) is a synthetic form of nitrothiazole with a broad range of applications as
an antiparasitic, antibacterial and antiviral agent. NTZ is a highly low aqueous soluble drug …
an antiparasitic, antibacterial and antiviral agent. NTZ is a highly low aqueous soluble drug …
Model-based optimization of cooling crystallization of active pharmaceutical ingredients undergoing thermal degradation
Many active pharmaceutical ingredients (APIs) undergo degradation at high temperature.
Optimum cooling profiles from first principle models usually do not consider this degradation …
Optimum cooling profiles from first principle models usually do not consider this degradation …
Asparagus officinalis Herb‐Derived Carbon Quantum Dots: Luminescent Probe for Medical Diagnostics
The utilization of natural materials for the synthesis of highly fluorescent carbon quantum
dots (CQDs) presents a sustainable approach to overcome the challenges associated with …
dots (CQDs) presents a sustainable approach to overcome the challenges associated with …
An approach to drug stability studies and shelf-life determination
E Tembhare, KR Gupta… - Archives of Current …, 2019 - publications.article4sub.com
The main objective of carrying out stability studies of the drug product is to establish shelf life
of drug during storage. Stability of drug is defined as “The capability of a particular …
of drug during storage. Stability of drug is defined as “The capability of a particular …
Monitoring forced degradation of drugs using silica coated AgNPs with surface-enhanced Raman scattering
Potential degradation products (DPs), even in small concentrations, can cause changes in
pharmacological and toxicological properties of a drug with a significant impact on product …
pharmacological and toxicological properties of a drug with a significant impact on product …