Update on the diagnosis of tuberculosis

I Kontsevaya, AM Cabibbe, DM Cirillo… - Clinical Microbiology …, 2023 - Elsevier
Background Tuberculosis remains a global public health threat, and the development of
rapid and precise diagnostic tools is the key to enabling the early start of treatment …

[HTML][HTML] Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis

A Grifoni, T Alonzi, G Alter, DMC Noonan… - Frontiers in …, 2023 - frontiersin.org
Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …

The ubiquitin ligase TRIM32 promotes the autophagic response to Mycobacterium tuberculosis infection in macrophages

A Romagnoli, M Di Rienzo, E Petruccioli, C Fusco… - Cell Death & …, 2023 - nature.com
Mycobacterium tuberculosis (Mtb) is known to evade host immune responses and persist in
macrophages for long periods. A mechanism that the host uses to combat Mtb is xenophagy …

Research tests for the diagnosis of tuberculosis infection

T Alonzi, F Repele, D Goletti - Expert Review of Molecular …, 2023 - Taylor & Francis
Introduction Despite huge efforts, tuberculosis (TB) is still a major public health threat
worldwide, it is estimated that a quarter of the global population is infected by …

Pulmonary Tuberculosis in Children: A Forgotten Disease?

U Pelosi, R Pintus, S Savasta, V Fanos - Microorganisms, 2023 - mdpi.com
Even today, tuberculosis in childhood is a disease that is often undiagnosed and
undertreated. In the absence of therapy with antituberculosis drugs, children in the first years …

Modelling differential diagnosis of febrile diseases with fuzzy cognitive map

O Obot, A John, I Udo, K Attai, E Johnson… - Tropical Medicine and …, 2023 - mdpi.com
The report of the World Health Organization (WHO) about the poor accessibility of people
living in low-to-middle-income countries to medical facilities and personnel has been a …

PET-CT-guided characterisation of progressive, preclinical tuberculosis infection and its association with low-level circulating Mycobacterium tuberculosis DNA in …

JW Kim, K Bowman, J Nazareth, J Lee… - The Lancet …, 2024 - thelancet.com
Background Incipient tuberculosis, a progressive state of Mycobacterium tuberculosis
infection with an increased risk of developing into tuberculosis disease, remains poorly …

[HTML][HTML] Evaluation of the immunomodulatory effects of interleukin-10 on peripheral blood immune cells of COVID-19 patients: Implication for COVID-19 therapy

S Najafi-Fard, E Petruccioli, C Farroni… - Frontiers in …, 2022 - frontiersin.org
Objective: Several therapies with immune-modulatory functions have been proposed to
reduce the overwhelmed inflammation associated with COVID-19. Here we investigated the …

[HTML][HTML] COVID-19 hampered diagnosis of TB infection in France, Italy, Spain and the United Kingdom

JM García-García, FX Blanc, D Buonsenso… - Archivos de …, 2022 - ncbi.nlm.nih.gov
We are still getting to grip with the impact that COVID-19 pandemic has had on the
tuberculosis (TB). 1–3 The Global Tuberculosis Network (GTN) described the first small …

Diagnostic value of chemiluminescence for urinary lipoarabinomannan antigen assay in active tuberculosis: insights from a retrospective study

L Huang, Y Niu, L Zhang, R Yang… - Frontiers in Cellular and …, 2023 - frontiersin.org
This study aimed to assess the efficacy of chemiluminescence-based urinary
lipoarabinomannan (LAM) antigen assay as a diagnostic tool for identifying active …