The water permeability of biological membranes has been a longstanding problem in
physiology, but the proteins responsible for this remained unknown until discovery of the …

Background Emerging evidence supports the view that (AQP) aquaporin water channels are
regulators of transcellular water flow. Consistent with their expression in most tissues, AQPs …

Membrane water transport is critically involved in brain volume homeostasis and in the
pathogenesis of brain edema. The cDNA encoding aquaporin-4 (AQP4) water channel …

Our understanding of the movement of water through cell membranes has been greatly
advanced by the discovery of a family of water-specific, membrane-channel proteins—the …

▪ Abstract The high water permeability characteristic of mammalian red cell membranes is
now known to be caused by the protein AQP1. This channel freely permits movement of …

Highlights (AQPs) are transmembrane proteins responsible for fast water movement across
cell membranes, including those of astrocytes. The expression and subcellular localization …

Water is the most important component of all organisms and is the basis of all life. That water
can pass through cell membranes has long been known-but how is the selective transport of …

Ion channels are membrane proteins that act as gated pathways for the movement of ions
across cell membranes. They play essential roles in the physiology of all cells. In recent …

Aquaporins (AQP) are integral membrane proteins that serve as channels in the transfer of
water, and in some cases, small solutes across the membrane. They are conserved in …

The topic of my talk, the aquaporins, is something that we have been studying in our lab for
the last 15 years. It is not something that I anticipated when starting my career. In fact, I am a …