Haemostasis and thrombosis are complex, multifactorial processes. There is an evolving
understanding of the mechanisms influencing vascular occlusion and the role of …

Some individuals with a particular disease-causing mutation or genotype fail to express
most if not all features of the disease in question, a phenomenon that is known as 'reduced …

Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2), has rapidly evolved into a sweeping pandemic. Its major …

Objective: To determine the spectrum of phenotypes linked to the ABO blood group system,
using genetic determinants of the ABO blood group system. Approach and Results: We …

Venous thromboembolism (VTE) includes deep vein thrombosis and pulmonary embolism,
and a combination of environmental and genetic risk factors contributes to VTE risk. Within …

The antigens of the ABO blood group system (A, B and H determinants, respectively) are
complex carbohydrate molecules on the extracellular surface of red blood cell membranes1 …

Background: Associations between vascular disease and ABO (H) blood groups have a long
history, but no consensus exists regarding its magnitude and significance, or whether it …

Background—ABO blood groups have been shown to be associated with increased risks of
venous thromboembolic and arterial disease. However, the reported magnitude of this …

It is well known that the ABO blood group exerts a major influence on hemostasis, as O
blood group individuals have lower von Willebrand factor and factor VIII levels than non-O …

Although a number of studies have demonstrated the influence of ABO blood group on
plasma levels of von Willebrand factor (VWF), the nature of this association and its clinical …