Drug memory reconsolidation: from molecular mechanisms to the clinical context

AL Milton - Translational Psychiatry, 2023 - nature.com
Since its rediscovery at the beginning of the 21st Century, memory reconsolidation has been
proposed to be a therapeutic target for reducing the impact of emotional memories that can …

Requisite role of dorsal raphe in contextual cocaine-memory reconsolidation

JL Ritchie, S Qi, RJ Christian, MJ Greenwood… - …, 2024 - Elsevier
Memory reconsolidation is a process by which labile drug memories are restabilized in long-
term memory stores, permitting their enduring control over drug-seeking behaviors. In the …

Ketamine ameliorates post-traumatic social avoidance by erasing the traumatic memory encoded in VTA-innervated BLA engram cells

M Li, XK Yang, J Yang, TX Li, C Cui, X Peng, J Lei… - Neuron, 2024 - cell.com
Erasing traumatic memory during memory reconsolidation is a promising retrieval-extinction
strategy for post-traumatic stress disorder (PTSD). Here, we developed an acute social …

A single dose of cocaine raises SV2A density in hippocampus of adolescent rats

R Rossi, SL Bærentzen, MB Thomsen… - Acta …, 2024 - cambridge.org
ObjectiveCocaine is a highly addictive psychostimulant that affects synaptic activity with
structural and functional adaptations of neurons. The transmembrane synaptic vesicle …

A locus coeruleus to dorsal hippocampus pathway mediates cue-induced reinstatement of opioid self-administration in male and female rats

T Markovic, J Higginbotham, B Ruyle… - …, 2024 - nature.com
Opioid use disorder is a chronic relapsing disorder encompassing misuse, dependence,
and addiction to opioid drugs. Long term maintenance of associations between the …

AMPA and NMDA receptors in dentate gyrus mediate memory for sucrose in two port discrimination task

S Sagarkar, N Bhat, D Rotti, NK Subhedar - Hippocampus, 2024 - Wiley Online Library
Although the phenomenon of memory formation and recall associated with the use of
psychotropic drugs has been extensively studied, mechanisms underlying memories for …

La neuroplasticidad como un potencial sustrato en abordajes terapéuticos del trastorno por consumo de sustancias de abuso: una revisión narrativa en modelos …

A Vega, DM San Juan, EAC Muñoz… - Revista inteRnacional de …, 2024 - riiad.org
Abstract Introduction: substance Use Disorder (SUD) is a public health problem that
presents a need for innovation in therapeutic approaches. Considering the vast evidence of …

Role of Corticotropin-Releasing Factor in Cocaine-Memory Reconsolidation

J Ritchie - 2024 - search.proquest.com
Environmental stimuli elicit drug craving and relapse in cocaine users by triggering the
retrieval of cocaine-associated contextual memories. Retrieval can also destabilize drug …