Simple Summary Nitric oxide is an important molecule that performs a variety of functions in
our bodies, especially in the cardiovascular system. In certain pathological conditions, such …

Endothelial dysfunction and consequent vasoconstriction are a common condition in
patients with hypertension and other cardiovascular diseases. Endothelial cells produce and …

Aims We determined whether decreased reactive oxygen species (ROS) production in the
aorta of pregnant spontaneously hypertensive rats (SHR) resulted in increased nitric oxide …

Hypertension is associated to impaired baroreflex sensitivity (BRS). In spontaneously
hypertensive rats (SHR), pregnancy reduces blood pressure, and this effect has been …

Objectives Over the past few years, the use of metallocomplexes for medical purposes has
considerably grown. Because of its favourable characteristics, ruthenium has taken a …

Aim This study aimed to evaluate the effects of Wortmannin, an inhibitor of
phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt), on aortic hyporeactivity to …

The endothelium is a monolayer of cells that extends on the vascular inner surface,
responsible for the modulation of vascular tone. By means of the release of nitric oxide (NO) …