Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient
are the major constraints during the development of new product. Various approaches have …

Abstract The Biopharmaceutics Classification System (BCS) has found widespread utility in
drug discovery, product development and drug product regulatory sciences. The …

Pharmaceutical co-crystals have gained significant attention in recent years as a promising
green and sustainable method for poorly soluble drugs to improve their solubility, stability …

Sahibzada MUK, Sadiq A, Faidah HS, et al. Drug Des Devel Ther. 2018; 12: 303–312. We,
the Editors and Publisher of Drug Design, Development and Therapy, have retracted the …

Crystal form can be crucial to the performance of a dosage form. This is especially true for
compounds that have intrinsic barriers to drug delivery, such as low aqueous solubility, slow …

The objective of present work was to develop novel sunscreen creams containing polymeric
nanoparticles (NPs) of morin. Polymeric NPs containing morin were prepared and …

ABSTRACT The FDA Biopharmaceutical Classification System guidance allows waivers for
in vivo bioavailability and bioequivalence studies for immediate‐release solid oral dosage …

We investigated the dissolution-modulating mechanism of alkalizers and polymers in
nanoemulsifying Gelucire 44/14 (GUC)-based solid dispersions (SDs) for controlled release …

The objective of the present study was to formulate surface solid dispersions (SSD) of
simvastatin to improve the aqueous solubility and dissolution rate to facilitate faster onset of …

Aceclofenac-loaded poly (vinyl-pyrrolidone)-based nanofiber formulations were prepared by
electrospinning to obtain drug-loaded orally disintegrating webs to enhance the solubility …