Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

Over 350 million individuals suffer from depression, a psychiatric illness classified as major
depressive disorder (MDD) with symptoms that include a loss of interest or pleasure in life …

Metabolic diseases, such as diabetes, obesity, and fatty liver disease, have now reached
epidemic proportions. Receptor tyrosine kinases (RTKs) are a family of cell surface …

Macrophage-stimulating protein (MSP), a soluble protein mainly synthesized by the liver, is
the only known ligand for recepteur d'origine nantais (RON), which is a member of the MET …

Background/Aims: Acetic acid (AcOH), a short-chain fatty acid, is reported to have some
beneficial effects on metabolism. Therefore, the aim of this study was to investigate the …

With an increasing body of literature covering RON receptor tyrosine kinase function in
different types of human cancers, it is becoming clear that RON has prominent roles in both …

Background Nonalcoholic fatty liver disease (NAFLD) is a common liver problem, including
both nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH). In this study …

Abstract Objects The roles of mRNA and microRNA (miRNA) are well known in many
diseases, including ischemic stroke; thus, integration analysis using mRNA and miRNA is …

Microglia are the primary immune cells residing in the central nervous system (CNS), where
they play essential roles in the health and disease. Depending on the CNS inflammatory …

Obesity promotes a chronic inflammatory state that is largely mediated by tissue-resident
macrophages as well as monocyte-derived macrophages. Diet-induced obesity (DIO) is a …