Animals have sophisticated mechanisms for coping with danger. Freezing is a unique state
that, upon threat detection, allows evidence to be gathered, response possibilities to be …

Although there is little direct evidence supporting that stress affects cancer incidence, it does
influence the evolution, dissemination and therapeutic outcomes of neoplasia, as shown in …

Clinical studies indicate that cannabidiol (CBD), the primary nonaddictive component of
cannabis that interacts with the serotonin (5-HT) 1A receptor, may possess analgesic and …

The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome …

A growing body of researches support a role for dysfunction of serotoninergic,
noradrenergic, and dopaminergic systems in the neurobiological processes involved in …

A model of the neuropsychology of anxiety is proposed. The model is based in the first
instance upon an analysis of the behavioural effects of the antianxiety drugs …

Research has elucidated causal links between stress exposure and the development of
anxiety disorders, but due to the limited use of female or sex-comparative animal models …

The beneficial effects of exercise on brain function have been demonstrated in animal
models and in a growing number of clinical studies on humans. There are multiple …

Anxiety is a psychological, physiological, and behavioral state induced in animals and
humans by a threat to well-being or survival, either actual or potential. It is characterized by …

This paper provides a brief review of the history, proposed pharmacological mechanisms,
safety issues, and clinical applications of the medicine 3, 4 …