Ischemic stroke is a major cause of death. Besides the direct damage resulting from oxygen
and glucose deprivation, sterile inflammation plays a pivotal role in increasing cellular …

High-mobility group box-1 (HMGB1) is a nuclear protein associated with early inflammatory
changes upon extracellular secretion expressed in various cells, including neurons and …

Stroke is a leading cause of death and disability worldwide. Several mechanisms are
involved in the pathogenesis of ischemic stroke (IS). The contributory role of the …

NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome inhibition and
autophagy induction attenuate inflammation and improve outcome in rodent models of …

Ischemic stroke often causes motor and cognitive deficits. Deregulated glia gap junction
communication, which is reflected by increased protein levels of glial fibrillary acidic protein …

The widespread application of ionizing radiation in industrial and medical fields leads to the
increased brain exposure to X-rays. Radiation brain injury (RBI) seriously affects health of …

Stroke is one of the highest incidence neurological disorder with great morbidity and
mortality rate. The secondary neuroinflammation contributed by microglial activation is a …

Acute ischemic stroke (AIS) is the 5 th leading cause of death and the leading cause of
neurological disability in the United States. The oxygen and glucose deprivation associated …

The mechanisms of brain protection during ischaemic reperfusion injury induced by
isoflurane (ISO) post‐conditioning are unclear. Myocyte enhancement factor 2 (MEF2D) has …

Stroke is the second leading cause of death worldwide and a leading cause of disability.
The innate immune response occurs immediately after cerebral ischemia, resulting in …