Understanding bacterial pathogenicity: a closer look at the journey of harmful microbes

J Soni, S Sinha, R Pandey - Frontiers in Microbiology, 2024 - frontiersin.org
Bacteria are the most prevalent form of microorganisms and are classified into two
categories based on their mode of existence: intracellular and extracellular. While most …

S-layers: the proteinaceous multifunctional armors of gram-positive pathogens

J Ravi, A Fioravanti - Frontiers in Microbiology, 2021 - frontiersin.org
S-layers are self-assembled crystalline 2D lattices enclosing the cell envelopes of several
bacteria and archaea. Despite their abundance, the landscape of S-layer structure and …

Architecture of the Sap S-layer of Bacillus anthracis revealed by integrative structural biology

A Sogues, K Leigh, EV Halingstad… - Proceedings of the …, 2024 - pnas.org
Bacillus anthracis is a spore-forming gram-positive bacterium responsible for anthrax, an
infectious disease with a high mortality rate and a target of concern due to bioterrorism and …

Structure and function of the EA1 surface layer of Bacillus anthracis

A Sogues, A Fioravanti, W Jonckheere… - Nature …, 2023 - nature.com
The Gram-positive spore-forming bacterium Bacillus anthracis is the causative agent of
anthrax, a deadly disease mostly affecting wildlife and livestock, as well as representing a …

[HTML][HTML] S-layer proteins as immune players: Tales from pathogenic and non-pathogenic bacteria

MH Assandri, M Malamud, FM Trejo… - Current Research in …, 2023 - Elsevier
In bacteria, as in other microorganisms, surface compounds interact with different pattern
recognition receptors expressed by host cells, which usually triggers a variety of cellular …

Giving a signal: how protein phosphorylation helps Bacillus navigate through different life stages

A Gangwal, N Kumar, N Sangwan… - FEMS Microbiology …, 2023 - academic.oup.com
Protein phosphorylation is a universal mechanism regulating a wide range of cellular
responses across all domains of life. The antagonistic activities of kinases and …

Genetic evidence for the interaction between Bacillus anthracis-encoded phage receptors and their cognate phage-encoded receptor binding proteins

S Forrest, S Ton, SL Sholes, S Harrison… - Frontiers in …, 2023 - frontiersin.org
Bacteriophages such as γ and AP50c have been shown to infect strains of Bacillus anthracis
with high specificity, and this feature has been exploited in the development of bacterial …

Single domain antibodies from camelids in the treatment of microbial infections

H De Greve, A Fioravanti - Frontiers in Immunology, 2024 - frontiersin.org
Infectious diseases continue to pose significant global health challenges. In addition to the
enduring burdens of ailments like malaria and HIV, the emergence of nosocomial outbreaks …

Ophthalmic implications of biological threat agents according to the chemical, biological, radiological, nuclear, and explosives framework

EH Curran, MD Devine, CD Hartley, Y Huang… - Frontiers in …, 2024 - frontiersin.org
As technology continues to evolve, the possibility for a wide range of dangers to people,
organizations, and countries escalate globally. The United States federal government …

Dynamic Profile of S-Layer Proteins Controls Surface Properties of Emetic Bacillus cereus AH187 Strain

C Boutonnet, S Lyonnais, B Alpha-Bazin… - Frontiers in …, 2022 - frontiersin.org
Many prokaryotes are covered by a two-dimensional array of proteinaceous subunits. This
surface layers (S-layer) is incompletely characterized for many microorganisms. Here, we …