Animal models of obesity and diabetes mellitus
More than one-third of the worldwide population is overweight or obese and therefore at risk
of developing type 2 diabetes mellitus. In order to mitigate this pandemic, safer and more …
of developing type 2 diabetes mellitus. In order to mitigate this pandemic, safer and more …
Towards fish lipid nutrigenomics: current state and prospects for fin-fish aquaculture
MJ Leaver, JM Bautista, BT Björnsson… - Reviews in Fisheries …, 2008 - Taylor & Francis
Lipids are the predominant source of energy for fish. The mechanisms by which fish allocate
energy from lipids for metabolism, development, growth, and reproduction are critical for …
energy from lipids for metabolism, development, growth, and reproduction are critical for …
Leptin signaling regulates glucose homeostasis, but not adipostasis, in the zebrafish
M Michel, PS Page-McCaw… - Proceedings of the …, 2016 - National Acad Sciences
Leptin is the primary adipostatic factor in mammals. Produced largely by adipocytes in
proportion to total adipose mass, the hormone informs the brain regarding total energy …
proportion to total adipose mass, the hormone informs the brain regarding total energy …
Evidence-based hormonal, mutational, and endocrine-disrupting chemical-induced zebrafish as an alternative model to study PCOS condition similar to mammalian …
Polycystic ovarian syndrome (PCOS) causes swollen ovaries in women at reproductive age
due to hormonal disorder with small cysts on the outer edges. The cause of the disorder is …
due to hormonal disorder with small cysts on the outer edges. The cause of the disorder is …
Zebrafish in endocrine systems: recent advances and implications for human disease
H Löhr, M Hammerschmidt - Annual review of physiology, 2011 - annualreviews.org
Since its introduction as a genetic vertebrate model system approximately 30 years ago, the
focus of zebrafish research has increasingly shifted to questions that are also relevant for …
focus of zebrafish research has increasingly shifted to questions that are also relevant for …
Retinal injury, growth factors, and cytokines converge on β-catenin and pStat3 signaling to stimulate retina regeneration
J Wan, XF Zhao, A Vojtek, D Goldman - Cell reports, 2014 - cell.com
Müller glia (MG) in the zebrafish retina respond to retinal injury by generating multipotent
progenitors for retinal repair. Here, we show that Insulin, Igf-1, and fibroblast growth factor …
progenitors for retinal repair. Here, we show that Insulin, Igf-1, and fibroblast growth factor …
Transgenerational inheritance of heart disorders caused by paternal bisphenol A exposure
M Lombó, C Fernández-Díez, S González-Rojo… - Environmental …, 2015 - Elsevier
Bisphenol A (BPA) is an endocrine disruptor used in manufacturing of plastic devices,
resulting in an ubiquitous presence in the environment linked to human infertility, obesity or …
resulting in an ubiquitous presence in the environment linked to human infertility, obesity or …
New insights into the signaling system and function of insulin in fish
MA Caruso, MA Sheridan - General and Comparative Endocrinology, 2011 - Elsevier
Fish have provided essential information about the structure, biosynthesis, evolution, and
function of insulin (INS) as well as about the structure, evolution, and mechanism of action of …
function of insulin (INS) as well as about the structure, evolution, and mechanism of action of …
On the diabetic menu: zebrafish as a model for pancreas development and function
Abstract Development of the vertebrate pancreas is a complex stepwise process comprising
regionalization, cell differentiation, and morphogenesis. Studies in zebrafish are contributing …
regionalization, cell differentiation, and morphogenesis. Studies in zebrafish are contributing …
Gonadal soma controls ovarian follicle proliferation through Gsdf in zebrafish
YL Yan, T Desvignes, R Bremiller… - Developmental …, 2017 - Wiley Online Library
Background: Aberrant signaling between germ cells and somatic cells can lead to
reproductive disease and depends on diffusible signals, including transforming growth factor …
reproductive disease and depends on diffusible signals, including transforming growth factor …