Introduction Immunotherapies for multiple sclerosis (MS) significantly decrease the risk of
new relapses. However, the chronic compartmentalized inflammation and …

Objective Patients with myelin oligodendrocyte glycoprotein antibody (MOG‐IgG)‐
associated disease (MOGAD) suffer from severe optic neuritis (ON) leading to retinal neuro …

Optic neuritis (ON) is an inflammatory attack of the optic nerve that leads to visual disability. It
is the most common optic neuropathy affecting healthy young adults, most commonly …

Background and Objective Erythropoietin (EPO) is a candidate neuroprotective drug. We
assessed its long-term safety and efficacy as an adjunct to methylprednisolone in patients …

Multiple sclerosis is a neurodegenerative disease associated with demyelination and
neuroinflammation in the central nervous system. There is an urgent need to develop …

Background and Objectives With the increasing use of visually evoked potentials (VEPs) as
quantitative outcome parameters for myelin in clinical trials, an in-depth understanding of …

Reliable biomarkers quantifying neurodegeneration and neuroinflammation in central
nervous system disorders such as Multiple Sclerosis, Alzheimer's dementia or Parkinson's …

Objective To explore prospectively through OCT the rate of retinal layer changes in
relapsing-remitting multiple sclerosis patients followed up on fingolimod or interferon, as …

Background: Diagnosis of multiple sclerosis (MS) may sometimes be ascertained at the time
of optic neuritis (ON) but other times require the advent of new disease activity. Objectives …

Purpose: Raman spectroscopy allows molecular changes to be quantified in vivo from the
tissues like the retina. Here we aimed to assess the metabolic changes in the retina of …