Spermatogonial stem cells for in vitro spermatogenesis and in vivo restoration of fertility
F Ibtisham, A Honaramooz - Cells, 2020 - mdpi.com
Spermatogonial stem cells (SSCs) are the only adult stem cells capable of passing genes
onto the next generation. SSCs also have the potential to provide important knowledge …
onto the next generation. SSCs also have the potential to provide important knowledge …
The study and manipulation of spermatogonial stem cells using animal models
Spermatogonial stem cells (SSCs) are a rare group of cells in the testis that undergo self-
renewal and complex sequences of differentiation to initiate and sustain spermatogenesis …
renewal and complex sequences of differentiation to initiate and sustain spermatogenesis …
Generation of a highly biomimetic organoid, including vasculature, resembling the native immature testis tissue
The creation of a testis organoid (artificial testis tissue) with sufficient resemblance to the
complex form and function of the innate testis remains challenging, especially using non …
complex form and function of the innate testis remains challenging, especially using non …
Culture supplementation of bFGF, GDNF, and LIF alters in vitro proliferation, colony formation, and pluripotency of neonatal porcine germ cells
Gonocytes in the neonatal testis have male germline stem cell properties and as such have
important potential applications in fertility preservation and regenerative medicine. Such …
important potential applications in fertility preservation and regenerative medicine. Such …
Using a testis regeneration model, FGF9, LIF, and SCF improve testis cord formation while RA enhances gonocyte survival
AH Awang-Junaidi, MA Fayaz, S Goldstein… - Cell and Tissue …, 2022 - Springer
Implantation of testis cell aggregates from various donors under the back skin of recipient
mice results in de novo formation of testis tissue. We used this implantation model to study …
mice results in de novo formation of testis tissue. We used this implantation model to study …
Long-term monitoring of donor xenogeneic testis tissue grafts and cell implants in recipient mice using ultrasound biomicroscopy
Testis tissue xenografting and testis cell aggregate implantation from various donor species
into recipient mice are novel models for the study and manipulation of testis formation and …
into recipient mice are novel models for the study and manipulation of testis formation and …
Brief exposure of neonatal testis cells to EGF or GDNF alters the regenerated tissue
AH Awang-Junaidi, MA Fayaz… - Reproduction and …, 2022 - raf.bioscientifica.com
We have previously shown that implantation of testis cell aggregates under the back skin of
immunodeficient mice results in de novo regeneration of testis tissue. We used this unique …
immunodeficient mice results in de novo regeneration of testis tissue. We used this unique …
Testicular quantitative ultrasound: A noninvasive monitoring method for evaluating spermatogenic function in busulfan‐induced testicular injury mouse models
WL Huang, L Ding, JH Yao, HT Hu, Y Gao, XY Xie… - Andrologia, 2021 - Wiley Online Library
Busulfan‐induced testicular injury mouse models are commonly used for experiments on
spermatogonial stem cell transplantation, treatments for azoospermia due to spermatogenic …
spermatogonial stem cell transplantation, treatments for azoospermia due to spermatogenic …
Theoretical and experimental strategies for preservation and restoration of male fertility
A Honaramooz - Human Reproductive and Prenatal Genetics, 2023 - Elsevier
Spermatogonial stem cells (SSCs) play a fundamental role in spermatogenesis and male
fertility. Recently, several theoretical or experimental SSC-based applications have emerged …
fertility. Recently, several theoretical or experimental SSC-based applications have emerged …
Neonatal Porcine Germ Cells Dedifferentiate and Display Osteogenic and Pluripotency Properties
Gonocytes are progenitors of spermatogonial stem cells in the neonatal testis. We have
previously shown that upon culturing, neonatal porcine gonocytes and their colonies …
previously shown that upon culturing, neonatal porcine gonocytes and their colonies …