[HTML][HTML] Implications of oncology trial design and uncertainties in efficacy-safety data on health technology assessments

D Trapani, K Tay-Teo, ME Tesch, F Roitberg… - Current …, 2022 - mdpi.com
Background: Advances in cancer medicines have resulted in tangible health impacts, but the
magnitude of benefits of approved cancer medicines could vary greatly. Health Technology …

Evolution of the joint International Atomic Energy Agency (IAEA), International Agency for Research on Cancer (IARC), and WHO cancer control assessments …

I Veljkovikj, AM Ilbawi, F Roitberg, S Luciani… - The Lancet …, 2022 - thelancet.com
Before 2005, cancer and other non-communicable diseases were not yet health and
development agenda priorities. Since the 2005 World Health Assembly Resolution, which …

[HTML][HTML] Grading of recommendations, assessment, development and evaluations concept 7: issues and insights linking guideline recommendations to trustworthy …

T Piggott, L Moja, K Jenei, T Kredo, N Skoetz… - Journal of Clinical …, 2024 - Elsevier
Objectives Guidelines and essential medicine lists (EMLs) bear similarities and differences
in the process that lead to decisions. Access to essential medicines is central to achieve …

Multicomponent processes to identify and prioritise low-value care in hospital settings: a scoping review

Z Tyack, H Carter, M Allen, S Senanayake… - BMJ open, 2024 - bmjopen.bmj.com
Objectives This scoping review mapped and synthesised original research that identified
low-value care in hospital settings as part of multicomponent processes. Design Scoping …

[HTML][HTML] GRADE Concept 7: Issues and Insights Linking Guideline Recommendations to Trustworthy Essential Medicine Lists

T Piggott, L Moja, K Jenei, T Kredo, N Skoetz… - Journal of Clinical …, 2024 - jclinepi.com
Objectives Guidelines and essential medicine lists (EMLs) bear similarities and differences
in the process that lead to decisions. Access to essential medicines is central to achieve …

[HTML][HTML] Evaluation of the ESMO-Magnitude of Clinical Benefit Scale version 1.1 (ESMO-MCBS v1. 1) for adjuvant radiotherapy in breast cancer

E Sapir, NI Cherny, RD Ennis, BD Smith, GL Smith… - ESMO open, 2023 - Elsevier
Background The European Society of Medical Oncology (ESMO) has suggested using the
ESMO-Magnitude of Clinical Benefit Scale (MCBS) to grade the magnitude of clinical benefit …

ESMO-Magnitude of Clinical Benefit Scale for haematological malignancies (ESMO-MCBS: H) version 1.0

B Kiesewetter, U Dafni, EGE de Vries, J Barriuso… - Annals of …, 2023 - Elsevier
Background The European Society for Medical Oncology (ESMO)-Magnitude of Clinical
Benefit Scale (MCBS) has been accepted as a robust tool to evaluate the magnitude of …

[HTML][HTML] Essential cancer medicines: adding feasibility to the magnitude of clinical benefit value chain

F Roitberg, T Amaral, NI Cherny, R Giuliani, NJ Latino… - Esmo Open, 2023 - Elsevier
Background Cancer is a global public health problem, requiring efficient health system
investments to deliver sustainable impact on population health. Access to medicines is a …

[HTML][HTML] WHO-ESMO collaboration in cancer control: policies into action to save lives

B Mikkelsen, S Peters - ESMO open, 2022 - esmoopen.com
There is now unique political and social momentum to prioritise health and well-being,
accentuated by the crises wrought by the COVID-19 pandemic. We have the opportunity to …

Is the Juice Worth the Squeeze? Overall Survival gain per unit treatment time as a metric of clinical benefit of systemic treatment in incurable cancers

N Joseph, V Bamunuarachchi, V Peiris, S Wijeskera… - medRxiv, 2023 - medrxiv.org
Introduction Novel systemic therapeutic options such as enzyme inhibitors and monoclonal
antibodies have transformed the practice of medical oncology in the recent past. However …