Implications of microbiota and bile acid in liver injury and regeneration
Studies examining the mechanisms by which the liver incurs injury and then regenerates
usually focus on factors and pathways directly within the liver, neglecting the signaling …
usually focus on factors and pathways directly within the liver, neglecting the signaling …
The role of gut microbiota in liver regeneration
Z Xu, N Jiang, Y Xiao, K Yuan, Z Wang - Frontiers in Immunology, 2022 - frontiersin.org
The liver has unique regeneration potential, which ensures the continuous dependence of
the human body on hepatic functions. As the composition and function of gut microbiota has …
the human body on hepatic functions. As the composition and function of gut microbiota has …
Gender differences in bile acids and microbiota in relationship with gender dissimilarity in steatosis induced by diet and FXR inactivation
This study aims to uncover how specific bacteria and bile acids (BAs) contribute to steatosis
induced by diet and farnesoid X receptor (FXR) deficiency in both genders. A control diet …
induced by diet and farnesoid X receptor (FXR) deficiency in both genders. A control diet …
[HTML][HTML] Retinoids in health and disease: a role for hepatic stellate cells in affecting retinoid levels
MW Haaker, AB Vaandrager, JB Helms - Biochimica et Biophysica Acta …, 2020 - Elsevier
Vitamin A (retinol) is important for normal growth, vision and reproduction. It has a role in the
immune response and the development of metabolic syndrome. Most of the retinol present …
immune response and the development of metabolic syndrome. Most of the retinol present …
Functional analysis of the relationship between intestinal microbiota and the expression of hepatic genes and pathways during the course of liver regeneration
Background & Aims The pathways regulating liver regeneration have been extensively
studied within the liver. However, the signaling contribution derived from the gut microbiota …
studied within the liver. However, the signaling contribution derived from the gut microbiota …
Targeting fatty acid metabolism for fibrotic disorders
Fibrosis is defined by abnormal accumulation of extracellular matrix, which can affect
virtually every organ system under diseased conditions. Fibrotic tissue remodeling often …
virtually every organ system under diseased conditions. Fibrotic tissue remodeling often …
Current knowledge about the effect of nutritional status, supplemented nutrition diet, and gut microbiota on hepatic ischemia-reperfusion and regeneration in liver …
ME Cornide-Petronio, AI Álvarez-Mercado… - Nutrients, 2020 - mdpi.com
Ischemia-reperfusion (I/R) injury is an unresolved problem in liver resection and
transplantation. The preexisting nutritional status related to the gut microbial profile might …
transplantation. The preexisting nutritional status related to the gut microbial profile might …
A selenium-containing ruthenium complex as a cancer radiosensitizer, rational design and the important role of ROS-mediated signalling
Z Deng, L Yu, W Cao, W Zheng, T Chen - Chemical Communications, 2015 - pubs.rsc.org
A novel selenium-containing ruthenium complex Ru (phtpy)(phenSe) Cl (ClO4)(phtpy= 4-
phenyl-2, 2′: 6′, 2′′-terpyridine, phenSe= 2-selenicimidazole [4, 5-f] 1, 10 …
phenyl-2, 2′: 6′, 2′′-terpyridine, phenSe= 2-selenicimidazole [4, 5-f] 1, 10 …
PPAR-gamma activation is associated with reduced liver ischemia-reperfusion injury and altered tissue-resident macrophages polarization in a mouse model
I Linares, K Farrokhi, J Echeverri, JM Kaths… - PLoS …, 2018 - journals.plos.org
Background PPAR-gamma (γ) is highly expressed in macrophages and its activation affects
their polarization. The effect of PPAR-γ activation on Kupffer cells (KCs) and liver ischemia …
their polarization. The effect of PPAR-γ activation on Kupffer cells (KCs) and liver ischemia …
[HTML][HTML] Liver regeneration and ethanol detoxification: a new link in YAP regulation of ALDH1A1 during alcohol‐related hepatocyte damage
J Zhou, C Sun, L Yang, J Wang, N Jn‐Simon… - The FASEB …, 2022 - ncbi.nlm.nih.gov
Abstract Yes‐associated protein (YAP), a central effector in the Hippo pathway, is involved in
the regulation of organ size, stem cell self‐renewal, and tissue regeneration. In this study …
the regulation of organ size, stem cell self‐renewal, and tissue regeneration. In this study …