The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Metabolic effects of oxytocin

SE McCormack, JE Blevins, EA Lawson - Endocrine reviews, 2020 - academic.oup.com
There is growing evidence that oxytocin (OXT), a hypothalamic hormone well recognized for
its effects in inducing parturition and lactation, has important metabolic effects in both sexes …

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration

C Elabd, W Cousin, P Upadhyayula, RY Chen… - Nature …, 2014 - nature.com
The regenerative capacity of skeletal muscle declines with age. Previous studies suggest
that this process can be reversed by exposure to young circulation; however, systemic age …

Evaluation of enzyme immunoassay and radioimmunoassay methods for the measurement of plasma oxytocin

A Szeto, PM McCabe, DA Nation, BA Tabak… - Psychosomatic …, 2011 - journals.lww.com
Objective: There is increased interest in measuring peripheral oxytocin levels to better
understand the role of this peptide in mammalian behavior, physiology, and disease. The …

Oxytocin reduces caloric intake in men

EA Lawson, DA Marengi, RL DeSanti, TM Holmes… - …, 2015 - Wiley Online Library
Objective Preclinical studies indicate that oxytocin is anorexigenic and has beneficial
metabolic effects. Oxytocin effects on nutrition and metabolism in humans are not well …

Oxytocin: crossing the bridge between basic science and pharmacotherapy

C Viero, I Shibuya, N Kitamura… - CNS neuroscience & …, 2010 - Wiley Online Library
Is oxytocin the hormone of happiness? Probably not. However, this small nine amino acid
peptide is involved in a wide variety of physiological and pathological functions such as …

Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats

N Deblon, C Veyrat-Durebex, L Bourgoin, A Caillon… - PloS one, 2011 - journals.plos.org
Apart from its role during labor and lactation, oxytocin is involved in several other functions.
Interestingly, oxytocin-and oxytocin receptor-deficient mice develop late-onset obesity with …

The effects of oxytocin on appetite regulation, food intake and metabolism in humans

L Kerem, EA Lawson - International Journal of Molecular Sciences, 2021 - mdpi.com
The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological
processes, including parturition, lactation, cell growth, wound healing, and social behavior …

Osteoblasts in osteoporosis: past, emerging, and future anabolic targets

PJ Marie, M Kassem - European journal of endocrinology, 2011 - academic.oup.com
Objective Age-related bone loss is associated with significant changes in bone remodeling
characterized by decreased trabecular and periosteal bone formation relative to bone …

Oxytocin is an anabolic bone hormone

R Tamma, G Colaianni, L Zhu… - Proceedings of the …, 2009 - National Acad Sciences
We report that oxytocin (OT), a primitive neurohypophyseal hormone, hitherto thought solely
to modulate lactation and social bonding, is a direct regulator of bone mass. Deletion of OT …