Pulmonary innate immune response determines the outcome of inflammation during pneumonia and sepsis-associated acute lung injury

V Kumar - Frontiers in immunology, 2020 - frontiersin.org
The lung is a primary organ for gas exchange in mammals that represents the largest
epithelial surface in direct contact with the external environment. It also serves as a crucial …

Food ingredients and active compounds against the coronavirus disease (COVID-19) pandemic: A comprehensive review

CM Galanakis, TMS Aldawoud, M Rizou, NJ Rowan… - Foods, 2020 - mdpi.com
As media reports have noted, the COVID-19 pandemic has accelerated market
mainstreaming of immune-boosting food bioactives, supplements, and nutraceuticals …

[HTML][HTML] β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective …

EJ Murphy, C Masterson, E Rezoagli, D O'Toole… - Science of the Total …, 2020 - Elsevier
Coronavirus pneumonia is accompanied by rapid virus replication, where a large number of
inflammatory cell infiltration and cytokine storm may lead to acute lung injury, acute …

STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion

B Wu, M Xu, C Fan, C Feng, Q Lu, H Lu… - Acta Pharmacologica …, 2022 - nature.com
Acute lung injury (ALI) is a common and devastating clinical disorder featured by excessive
inflammatory responses. Stimulator of interferon genes (STING) is an indispensable …

Brain–lung interactions and mechanical ventilation in patients with isolated brain injury

M Ziaka, A Exadaktylos - Critical care, 2021 - Springer
During the last decade, experimental and clinical studies have demonstrated that isolated
acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and …

Acute exacerbation of interstitial lung disease associated with rheumatic disease

F Luppi, M Sebastiani, C Salvarani… - Nature Reviews …, 2022 - nature.com
Interstitial lung disease (ILD) is a cause of morbidity and mortality in patients with rheumatic
diseases, such as connective-tissue diseases, rheumatoid arthritis and systemic vasculitis …

Prone position for acute respiratory failure in adults

R Bloomfield, DW Noble… - Cochrane database of …, 2015 - cochranelibrary.com
Background Acute hypoxaemia de novo or on a background of chronic hypoxaemia is a
common reason for admission to intensive care and for provision of mechanical ventilation …

[HTML][HTML] SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury

D Kurundkar, AR Kurundkar, NB Bone, EJ Becker Jr… - JCI insight, 2019 - ncbi.nlm.nih.gov
Acute lung injury (ALI) is characterized by exuberant proinflammatory responses and
mitochondrial dysfunction. However, the link between mitochondrial dysfunction and …

Long-term outcome after the acute respiratory distress syndrome: different from general critical illness?

T Bein, S Weber-Carstens… - Current opinion in critical …, 2018 - journals.lww.com
Surviving ARDS is associated with a long-term substantial reduction in health-related quality
of life and such a reduction does not differ from findings in patients surviving other critical …

Prevention and treatment of acute lung injury with time-controlled adaptive ventilation: physiologically informed modification of airway pressure release ventilation

GF Nieman, LA Gatto, P Andrews, J Satalin… - Annals of intensive …, 2020 - Springer
Mortality in acute respiratory distress syndrome (ARDS) remains unacceptably high at
approximately 39%. One of the only treatments is supportive: mechanical ventilation …