Animal models of depression: what can they teach us about the human disease?
Depression is apparently the most common psychiatric disease among the mood disorders
affecting about 10% of the adult population. The etiology and pathogenesis of depression …
affecting about 10% of the adult population. The etiology and pathogenesis of depression …
Role of neuropeptides in anxiety, stress, and depression: from animals to humans
Major depression, with its strikingly high prevalence, is the most common cause of disability
in communities of Western type, according to data of the World Health Organization. Stress …
in communities of Western type, according to data of the World Health Organization. Stress …
Potential gut–brain mechanisms behind adverse mental health outcomes of bariatric surgery
RM Brown, E Guerrero-Hreins, WA Brown… - Nature Reviews …, 2021 - nature.com
Bariatric surgery induces sustained weight loss and metabolic benefits via notable effects on
the gut–brain axis that lead to alterations in the neuroendocrine regulation of appetite and …
the gut–brain axis that lead to alterations in the neuroendocrine regulation of appetite and …
[HTML][HTML] Targeting the neuropeptide Y system in stress-related psychiatric disorders
NM Enman, EL Sabban, P McGonigle… - Neurobiology of …, 2015 - Elsevier
Repeated, extreme, or traumatic stressors can elicit pathological effects leading to many
negative physical and psychological outcomes. Stressors can precipitate the onset of …
negative physical and psychological outcomes. Stressors can precipitate the onset of …
Neuropeptide Y and posttraumatic stress disorder
R Sah, TD Geracioti - Molecular psychiatry, 2013 - nature.com
Resiliency to the adverse effects of extraordinary emotional trauma on the brain varies within
the human population. Accordingly, some people cope better than others with traumatic …
the human population. Accordingly, some people cope better than others with traumatic …
[HTML][HTML] Reinstating olfactory bulb-derived limbic gamma oscillations alleviates depression-like behavioral deficits in rodents
Q Li, Y Takeuchi, J Wang, L Gellért, L Barcsai… - Neuron, 2023 - cell.com
Although the etiology of major depressive disorder remains poorly understood, reduced
gamma oscillations is an emerging biomarker. Olfactory bulbectomy, an established model …
gamma oscillations is an emerging biomarker. Olfactory bulbectomy, an established model …
The olfactory bulbectomized rat as a model of depression: the hippocampal pathway
In rodents, the removal of the olfactory bulbs (OBs), ie olfactory bulbectomy (OBX), results in
numerous alterations in neurotransmitter, endocrine and immune systems, as well as …
numerous alterations in neurotransmitter, endocrine and immune systems, as well as …
The microbiota-gut-brain axis in pathogenesis of depression: A narrative review
H Yao, D Zhang, H Yu, H Shen, H Liu, F Meng… - Physiology & …, 2023 - Elsevier
The microbiota-gut-brain axis is a bidirectional regulatory pathway between the brain and
the gastrointestinal tract, which plays an important role in maintain homeostasis. Gut …
the gastrointestinal tract, which plays an important role in maintain homeostasis. Gut …
Neuropeptide Y in the medial habenula alleviates migraine-like behaviors through the Y1 receptor
C Yang, Z Gong, X Zhang, S Miao, B Li, W Xie… - The Journal of …, 2023 - Springer
Background Migraine is a highly disabling health burden with multiple symptoms; however,
it remains undertreated because of an inadequate understanding of its neural mechanisms …
it remains undertreated because of an inadequate understanding of its neural mechanisms …
Basolateral amygdala neuropeptide Y system modulates binge ethanol consumption
SL Robinson, SC Bendrath, EM Yates… - …, 2024 - nature.com
Neuropeptide Y (NPY) signaling regulation of corticolimbic communication is known to
modulate binge-like ethanol consumption in rodents. In this work we sought to assess the …
modulate binge-like ethanol consumption in rodents. In this work we sought to assess the …