Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …

For more than 50 years, evidence has accumulated that inflammation contributes to the
pathogenesis of hypertension. Immune cells have been observed in vessels and kidneys of …

Hypertension is a global health problem, with> 1.3 billion individuals with high blood
pressure worldwide. In this Review, we present an inflammatory paradigm for hypertension …

Inflammasomes are components of the innate immune response that have recently emerged
as crucial controllers of tissue homeostasis. In particular, the nucleotide-binding domain …

Alzheimer's disease, the most common type of dementia among older adults, currently
cannot be prevented or effectively treated. Only a very small percentage of Alzheimer's …

Emerging evidence has supported a role of inflammation and immunity in the genesis of
hypertension. In humans and experimental models of hypertension, cells of the innate and …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals that
have hypertension or cardiovascular comorbidities have an elevated risk of serious …

Significance: Salt sensitivity of blood pressure (SSBP) is an independent risk factor for
mortality and morbidity due to cardiovascular disease, and disproportionately affects blacks …

Heart failure with preserved ejection fraction (HFpEF) now accounts for the majority of new
heart failure diagnoses and continues to increase in prevalence in the United States …

Abstract Purpose of Review This review summarizes the involvement of inflammaging in
vascular damage with focus on the epigenetic mechanisms by which inflammaging-induced …