Brown adipose tissue—a translational perspective

AC Carpentier, DP Blondin, F Haman… - Endocrine …, 2023 - academic.oup.com
Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

Sex differences in body composition

MA Bredella - Sex and gender factors affecting metabolic …, 2017 - Springer
Body composition differs between men and women. Men have more lean mass, and women
have more fat mass than men. Men are more likely to accumulate adipose tissue around the …

Estrogen deficiency and the origin of obesity during menopause

F Lizcano, G Guzmán - BioMed research international, 2014 - Wiley Online Library
Sex hormones strongly influence body fat distribution and adipocyte differentiation.
Estrogens and testosterone differentially affect adipocyte physiology, but the importance of …

Estrogen receptors and the metabolic network

RPA Barros, JÅ Gustafsson - Cell metabolism, 2011 - cell.com
The metabolic syndrome has reached pandemic level worldwide, and evidence is that
estradiol plays a key role in its development. The discovery of the second estrogen receptor …

Global analysis of plasma lipids identifies liver-derived acylcarnitines as a fuel source for brown fat thermogenesis

J Simcox, G Geoghegan, JA Maschek, CL Bensard… - Cell metabolism, 2017 - cell.com
Cold-induced thermogenesis is an energy-demanding process that protects endotherms
against a reduction in ambient temperature. Using non-targeted liquid chromatography …

[HTML][HTML] Obesity: a neuroimmunometabolic perspective

CM Larabee, OC Neely, AI Domingos - Nature Reviews Endocrinology, 2020 - nature.com
Neuroimmunology and immunometabolism are burgeoning topics of study, but the
intersection of these two fields is scarcely considered. This interplay is particularly prevalent …

[HTML][HTML] Unraveling female reproductive senescence to enhance healthy longevity

L Dong, DBL Teh, BK Kennedy, Z Huang - Cell Research, 2023 - nature.com
In a society where women often want successful careers and equal opportunities to men, the
early nature of ovarian aging often forces women to make difficult life choices between …

Brown adipose tissue in adult humans: a metabolic renaissance

P Lee, MM Swarbrick, KKY Ho - Endocrine reviews, 2013 - academic.oup.com
Brown adipose tissue (BAT) plays a key role in energy homeostasis and thermogenesis in
animals, conferring protection against diet-induced obesity and hypothermia through the …

Gender differences in diabetic kidney disease: focus on hormonal, genetic and clinical factors

A Giandalia, AE Giuffrida, G Gembillo… - International journal of …, 2021 - mdpi.com
Diabetic kidney disease (DKD) is one of the most serious complications of both type 1
(T1DM) and type 2 diabetes mellitus (T2DM). Current guidelines recommend a personalized …

Sex differences in brown adipose tissue function: sex hormones, glucocorticoids, and their crosstalk

K Kaikaew, A Grefhorst, JA Visser - Frontiers in endocrinology, 2021 - frontiersin.org
Excessive fat accumulation in the body causes overweight and obesity. To date, research
has confirmed that there are two types of adipose tissue with opposing functions: lipid …