• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

A number of clinical studies have reported that diabetes mellitus (DM) is an independent risk
factor for Atrial fibrillation (AF). After adjustment for other known risk factors including age …

Diabetes mellitus is one of the prime risk factors for cardiovascular complications and is
linked with high morbidity and mortality. Diabetic cardiomyopathy (DCM) often manifests as …

Aim: Myocardial fibrosis is a well-established cause of increased myocardial stiffness and
subsequent diastolic dysfunction in the diabetic heart. The molecular regulators that drive …

Atrial fibrillation (AF) is prevalent in common conditions and acquired forms of heart disease,
including diabetes mellitus (DM), hypertension, cardiac hypertrophy, and heart failure. AF is …

Heart failure (HF) and type 2 diabetes mellitus (T2DM) represent two important public health
problems, and despite improvements in the management of both diseases, they are …

Hormones are potent endo-, para-, and autocrine endogenous regulators of the function of
multiple organs, including the heart. Endocrine dysfunction promotes a number of …

Atrial fibrillation (AF) is prevalent in diabetes mellitus (DM); however, the basis for this is
unknown. This study investigated AF susceptibility and atrial electrophysiology in type 1 …

Background Atrial fibrillation (AF) is highly prevalent in diabetes mellitus (DM), yet the basis
for this finding is poorly understood. Type 2 DM may be associated with unique patterns of …

Background Calcium/calmodulin-dependent kinase II-delta (CaMKIIδ) activity is enhanced
during hyperglycemia and has been shown to alter intracellular calcium handling in …